Results 311 to 320 of about 867,204 (374)

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Low wall shear stress predominates at sites of abdominal aortic aneurysm rupture.

Journal of Vascular Surgery, 2015
A. Boyd, D. Kuhn, Richard J. Lozowy, G. Kulbisky   +3 more
semanticscholar   +1 more source

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

The FEBS Journal, EarlyView.
The damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel) compared with the wild‐type littermates. These changes are accompanied by a wide‐ranging impact, including phenotypical (middle panel) and molecular (right panel) changes ...
Sanna‐Maria Karppinen, Miki Aho, Zoltan Szabo, Johanna Magga, Laura Vainio, Erhe Gao, Paul Janmey, Lauri Eklund, Karolina Rasi, Ilkka Miinalainen, Lynn Y. Sakai, Lasse Pakanen, Heikki Huikuri, Juhani Junttila, Risto Kerkelä, Taina Pihlajaniemi   +15 more
wiley   +1 more source

The impact of the COVID‐19 pandemic on longitudinal trends of surgical mortality and inpatient quality of care in Ontario, Canada

Journal of Advanced Nursing, EarlyView.
Abstract Aims Previous studies have shown the COVID‐19 pandemic was associated with reductions in volume across a spectrum of non‐SARS‐CoV‐2 hospitalizations. In the present study, we examine the impact of the pandemic on patient safety and quality of care. Design This is a retrospective population‐based study of discharge abstracts. Methods We applied
Steven Habbous, Maggie Ford, Stacey Bar‐Ziv, Terri Donovan, Erik Hellsten   +4 more
wiley   +1 more source

Sudden Death in the Young: A Nationwide Prospective Epidemiological Study of Sudden Death in Young People Aged 1–35 Years in the Mediterranean Island of Cyprus

Journal of Cardiovascular Electrophysiology, EarlyView.
Epidemiological profile of sudden death in young individuals aged 1–35 years in Cyprus: Cardiac causes account for the majority of cases, with cardiomyopathies being the leading cause of sudden cardiac death. A high proportion of unexplained deaths highlights the need for further targeted genetic evaluation.
Loizos Antoniades, Constantinos Antoniades, Hera Moustra Heracleous, Georgia Daniel, Alexandros Protonotarios, Aris Anastasakis, Adalena Tsatsoppoulou, Petros Agathangelou   +7 more
wiley   +1 more source

Increased 18F-FDG uptake is predictive of rupture in a novel rat abdominal aortic aneurysm rupture model.

Annals of Surgery, 2015
S. English, M. Piert, J. Diaz, David Gordon, Abhijit Ghosh, Louis G DʼAlecy, S. Whitesall, Ashish K Sharma, Elise DeRoo, T. Watt, Gang Su, P. Henke, J. Eliason, G. Ailawadi, G. Upchurch   +14 more
semanticscholar   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Rupture of an abdominal aortic aneurysm causes priming of phagocytic oxidative burst

, 1997
Thomas F. Lindsay, Nader Memari, Anand Ghanekar, Paul M. Walker, Alex Romaschin   +4 more
openalex   +1 more source

Morphological features of serosa‐associated lymphoid clusters of the rat parietal pleura: Exploring a relatively unexplored system

Journal of Anatomy, EarlyView.
This study explored serosa‐associated lymphoid clusters in rat pleura (pSALCs), identifying their distribution and categorizing them into four morphological types. Data provided by this study form the basis for future morphological comparisons with humans and the potential to extrapolate functional characteristics of pSALCs from experimental studies in
Rosa E. Lagerwerf, Claire Mackaaij, Frieke Kuper, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +4 more
wiley   +1 more source