Results 121 to 130 of about 36,295 (248)

Nonsteroidal antiinflammatory drugs are associated with increased aortic stiffness

open access: yesVascular Health and Risk Management, 2005
Martin Claridge1, Simon Hobbs1, Clive Quick2, Nick Day3, Andrew Bradbury1, Teun Wilmink11Department of Vascular Surgery, University of Birmingham, Birmingham Heartlands Hospital Birmingham, UK; 2Department of Surgery, Hinchingbrooke Hospital, Huntingdon,
Martin Claridge   +5 more
doaj  

50% body weight loading reduces stature increases and lumbar disc expansion from 4 h hyper‐buoyancy floatation versus 15 min sitting upright

open access: yesExperimental Physiology, EarlyView.
Abstract Microgravity is associated with stature increases, back pain and post‐flight intervertebral disc (IVD) herniation. This study aims to determine whether 30 s seated 50% body weight (BW) axial loading is comparable to 15 min sitting upright in 1 g upon changes in stature, anterior lumbar IVD height (via ultrasound), passive vertebral stiffness ...
David Marcos‐Lorenzo   +6 more
wiley   +1 more source

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

open access: yesExperimental Physiology, EarlyView.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier   +5 more
wiley   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu   +4 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

open access: yesExperimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

Influence of menstrual cycle phase on inflammatory and vascular responses to acute passive heating in healthy young women

open access: yesExperimental Physiology, EarlyView.
Abstract The aim of this study was to determine whether inflammatory and vascular responses to passive heating differ between the early follicular phase (EFP) and the mid‐luteal phase (MLP) of the menstrual cycle. Ten healthy, naturally menstruating females (26 ± 3 years of age; body mass index 21.4 ± 1.9 kg/m2) were assessed during EFP and MLP ...
Yunuo Su   +3 more
wiley   +1 more source

Association of Physical Activity With Aortic Stiffness in the Jackson Heart Study. [PDF]

open access: yesAm J Hypertens
Patrick Z   +5 more
europepmc   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

open access: yesExperimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson   +2 more
wiley   +1 more source

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