Smooth Muscle Cell Specific Activity of SGK-1 Alters Aortic Stiffness and Abdominal Aortic Aneurysm Growth. [PDF]
Anderson M +9 more
europepmc +1 more source
Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo +5 more
wiley +1 more source
Assessment of aortic stiffness determinants including smoking status by a novel semiautomatic doppler ultrasound. [PDF]
Lin H +5 more
europepmc +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Development of an interpretable machine learning model for early prediction of aortic stiffness risk in health examination populations. [PDF]
Zhou Z +7 more
europepmc +1 more source
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source
Circulating vascular biomarkers in relation to physiological indices of aortic stiffness and endothelial function in hypertension. [PDF]
Jekell A, Ekholm M, Kahan T, Lundwall K.
europepmc +1 more source
Aortic Stiffness and Cerebral Blood Flow [PDF]
openaire +2 more sources
Acute intermittent hypercapnic hypoxia augments left ventricular contractility
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall +8 more
wiley +1 more source
Relation of carotid-to-femoral pulse wave velocity to aortic stiffness and total arterial compliance in healthy individuals. [PDF]
Çelikbudak Orhon C +9 more
europepmc +1 more source

