Effect of FluoRoquinolones on Aortic Growth, aortic stIffness and wave refLEctionS (FRAGILES study). [PDF]
Gardikioti V +8 more
europepmc +1 more source
MYH11 variants in thoracic aortic aneurysm pathophysiology: From bench to bedside
Thoracic aortic aneurysms and dissections (TAAD) are often asymptomatic until rupture or dissection, which are associated with high mortality. Around 20% of cases of TAAD show familial segregation; some of these are linked to pathogenic variants in vascular smooth muscle cell contractile genes, like MYH11.
Aria Atash +6 more
wiley +1 more source
Investigating the Association of Aortic Stiffness and Phase Angle with the Clinical Course of Rheumatoid Arthritis. [PDF]
Movassaghi S +5 more
europepmc +1 more source
ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD), recently redefined from non‐alcoholic fatty liver disease (NAFLD), highlights the central role of metabolic dysfunction in its pathophysiology. The L‐α‐lysophosphatidylinositol/G protein‐coupled receptor 55 (LPI/GPR55) axis, an element of the endocannabinoidome, has emerged as a key
Jerome Lian +3 more
wiley +1 more source
Association of Aortic Stiffness with Heart Failure with Preserved Ejection Fraction: New Insights into the Ventriculoarterial Connection. [PDF]
Bremerich J, Pradella M.
europepmc +1 more source
This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan +11 more
wiley +1 more source
Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction. [PDF]
Schulz A +12 more
europepmc +1 more source
Aortic stiffness in hypertrophic cardiomyopathy.
O, Uz +4 more
openaire +1 more source
Association of Aortic Stiffness and Pressure Pulsatility With Noninvasive Estimates of Hepatic Steatosis and Fibrosis: The Framingham Heart Study. [PDF]
Cooper LL +7 more
europepmc +1 more source
Assessing pressure wave components for aortic stiffness monitoring through spectral regression learning. [PDF]
Aghilinejad A, Gharib M.
europepmc +1 more source

