Results 241 to 250 of about 71,731 (296)

Effect of FluoRoquinolones on Aortic Growth, aortic stIffness and wave refLEctionS (FRAGILES study). [PDF]

open access: yesLife (Basel)
Gardikioti V   +8 more
europepmc   +1 more source

MYH11 variants in thoracic aortic aneurysm pathophysiology: From bench to bedside

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.
Thoracic aortic aneurysms and dissections (TAAD) are often asymptomatic until rupture or dissection, which are associated with high mortality. Around 20% of cases of TAAD show familial segregation; some of these are linked to pathogenic variants in vascular smooth muscle cell contractile genes, like MYH11.
Aria Atash   +6 more
wiley   +1 more source

Investigating the Association of Aortic Stiffness and Phase Angle with the Clinical Course of Rheumatoid Arthritis. [PDF]

open access: yesAdv Biomed Res
Movassaghi S   +5 more
europepmc   +1 more source

Targeting the LPI/GPR55 Axis in MAFLD and MASH: Novel Insights, Therapeutic Strategies and Future Directions

open access: yesLiver International, Volume 46, Issue 4, April 2026.
ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD), recently redefined from non‐alcoholic fatty liver disease (NAFLD), highlights the central role of metabolic dysfunction in its pathophysiology. The L‐α‐lysophosphatidylinositol/G protein‐coupled receptor 55 (LPI/GPR55) axis, an element of the endocannabinoidome, has emerged as a key
Jerome Lian   +3 more
wiley   +1 more source

ZNF384‐Driven Fibulin‐1 Exacerbates Vascular Stiffness via TGF‐β/Smad3‐Mediated Senescence and Fibrosis

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan   +11 more
wiley   +1 more source

Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction. [PDF]

open access: yesRadiol Cardiothorac Imaging
Schulz A   +12 more
europepmc   +1 more source

Aortic stiffness in hypertrophic cardiomyopathy.

open access: yesEuropean review for medical and pharmacological sciences, 2015
O, Uz   +4 more
openaire   +1 more source

Association of Aortic Stiffness and Pressure Pulsatility With Noninvasive Estimates of Hepatic Steatosis and Fibrosis: The Framingham Heart Study. [PDF]

open access: yesArterioscler Thromb Vasc Biol
Cooper LL   +7 more
europepmc   +1 more source

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