Results 31 to 40 of about 1,753,663 (307)

Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost-effectiveness. [PDF]

, 2013
BACKGROUND: Small abdominal aortic aneurysms (AAAs; 3.0-5.4 cm in diameter) are usually asymptomatic and managed by regular ultrasound surveillance until they grow to a diameter threshold (commonly 5.5 cm) at which surgical intervention is considered ...
Bown, MJ, JT Powell, Sweeting, M., Glover, M, MJ Sweeting, MJ Buxton, Powell, J, MJ Bown, Bown, M, Glover, MJ, Powell, JT, Sweeting, M, the RESCAN collaborators, Brown, L., LC Brown, LG Kim, Thompson, S., Kim, LG, Bown, M., Glover, Matthew, Sweeting, MJ, Brown, LC, Buxton, M, Kim, L., Thompson, SG, Thompson, S, SG Thompson, Kim, L, Buxton, MJ, MJ Glover, Brown, L   +30 more
core   +1 more source

High-intensity interval exercise training before abdominal aortic aneurysm repair (HIT-AAA): protocol for a randomised controlled feasibility trial [PDF]

, 2014
Introduction: In patients with large abdominal aortic aneurysm (AAA), open surgical or endovascular aneurysm repair procedures are often used to minimise the risk of aneurysm-related rupture and death; however, aneurysm repair itself carries a high risk.
Kerr, K., Kerr, Karen, Weston, Matthew; id_orcid, Tew, G.A., Tew, Garry A, Tew, Garry, Danjoux, Gerard, Batterham, A.M., Batterham, Alan M, Alan M Batterham, Gray, Joanne, Martin, D., Danjoux, Gerard R., Nawaz, Shah, Matthew Weston, Yates, David, Weston, M., Elke Kothmann, Tew, G. A. (Garry), Gerard Danjoux, Gray, J., Weston, Matthew, Yates, D., Garry A Tew, Kothmann, Elke, Martin, Denis, Denis Martin, Martin, Denis; id_orcid, Nawaz, S., Batterham, Alan, Shah Nawaz, Kothmann, E., Joanne Gray, Danjoux, G., David Yates, Karen Kerr   +35 more
core   +1 more source

Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis

Scientific Reports
To investigate the association between area deprivation index (ADI) and aortic valve replacement (AVR) in patients with severe aortic stenosis (AS). Patients aged 40–95 years with severe AS confirmed by echocardiography were included.
Chirag Ram, Sameh Yousef, Wei-Guo Ma, Ishani Vallabhajosyula, Saket Singh, Ritu Agarwal, Rita K. Milewski, Roland Assi, Prakash A. Patel, Matthew Williams, Arnar Geirsson, Prashanth Vallabhajosyula   +11 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Hospital Incidence and In‐Hospital Mortality of Surgically and Interventionally Treated Aortic Dissections: Secondary Data Analysis of the Nationwide German Diagnosis‐Related Group Statistics From 2006 to 2014

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Population‐based data about the incidence and mortality of patients with aortic dissections (ADs) are sparse. Therefore, the hospital incidence and in‐hospital mortality of patients undergoing open or endovascular surgery for type A ADs (TAADs)
Benedikt Reutersberg, Michael Salvermoser, Matthias Trenner, Sarah Geisbüsch, Alexander Zimmermann, Hans‐Henning Eckstein, Andreas Kuehnl   +6 more
doaj   +1 more source

The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. [PDF]

, 2015
Introduction Chronic thoracic aortic aneurysm (CTAA) affecting the arch or descending aorta is an indolent but life-threatening condition with a rising prevalence as the UK population ages.
Catarino, P., ETTAA Collaborators, Gray, J, Vallabhaneni, S, Vale, L., Vallabhaneni, Srinivasa, Cook, A., Moorjani, N, Moorjani, Narain, Vale, Luke, Sharples, L., Gray, Joanne, Cook, Andrew, Elefteriades, JA, Sastry, P., Sharples, Linda, Vallabhaneni, S. R., Sastry, P, Moorjani, N., Hughes, V., Elefteriades, John, Cook, A, Catarino, Pedro, Hughes, V, Elefteriades, J., Hayes, P, on behalf of the ETTAA collaborators, Thompson, M., Hayes, P., Gray, J., Vale, L, Large, Stephen, Catarino, P, Thompson, Matt, Sharples, L, Hughes, Victoria, Elefteriades, John A, Hayes, Paul, Thompson, M, Sastry, Priya, Large, Stephen R, Large, SR, Large, S. R.   +42 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Association of surgeon sex with postoperative adverse outcomes in adult cardiac surgery: a nationwide cohort study

Journal of Cardiothoracic Surgery
Background Sex-based differences in outcomes after cardiac surgery are consistently reported, with women frequently experiencing higher postoperative morbidity and mortality.
Melanie Arnreiter, Alexandra Kaider, Marija Pljakova, Philipp Angleitner, Kira Osipenko, Nicole Klaus, Daniel Zimpfer, Andreas Zuckermann, Mario Gaudino, Sigrid Sandner   +9 more
doaj   +1 more source

Urgent endovascular aortic dissection repair in a Marfan patient during COVID‐19 pandemic

Clinical Case Reports, 2021
Although Thoracic Endovascular Aortic Repair is usually applied to patients without connective tissue disorders, our case shows its potential for complicated type B aortic dissection in a Marfan patient as a feasible alternative to open redo surgery with
Xun Yuan, Mireya Castro Verdes, Massimo Capoccia, Ulrich Rosendahl, Christoph A. Nienaber   +4 more
doaj   +1 more source