Results 71 to 80 of about 328,272 (309)

Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease

open access: yes, 2013
BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease. METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43+/-18years) with ...
Aydin, A.   +15 more
core   +1 more source

A Case Report of a Mediastinal Fistula with Liver Abscesses as a Complication of Aortic Valve Replacement Surgery [PDF]

open access: yes, 2017
We report a case of mediastinal fistula with liver abscesses detected by thoracic and abdominal computed tomography as a complication of aortic valve replacement ...
Eduardo Bossone   +3 more
core   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu   +11 more
wiley   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

open access: yesAdvanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li   +11 more
wiley   +1 more source

Predicting pressure gradient using artificial intelligence for transcatheter aortic valve replacementCentral MessagePerspective

open access: yesJTCVS Techniques
Objective: After transcatheter aortic valve replacement, the mean transvalvular pressure gradient indicates the effectiveness of the therapy. The objective is to develop artificial intelligence to predict the post–transcatheter aortic valve replacement ...
Anoushka Dasi, BS   +5 more
doaj   +1 more source

Follow-Up Report of Patients With Moderate Aortic Valve Regurgitation After Cardiac Surgery [PDF]

open access: yesTexas Heart Institute Journal
Background: The appropriateness of aortic valve surgery for patients with moderate aortic valve regurgitation undergoing coronary artery bypass graft (CABG), mitral valve replacement (MVR), or both is uncertain.
Arezou Zoroufian, MD   +6 more
doaj   +1 more source

Minimally Invasive Mitral Valve Surgery II: Surgical Technique and Postoperative Management. [PDF]

open access: yes, 2016
Techniques for minimally invasive mitral valve repair and replacement continue to evolve. This expert opinion, the second of a 3-part series, outlines current best practices for nonrobotic, minimally invasive mitral valve procedures, and for ...
Agnihotri, Arvind K   +25 more
core   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

open access: yesAdvanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue   +17 more
wiley   +1 more source

Infective endocarditis of quadricuspid aortic valve

open access: yesJournal of Cardiothoracic Surgery, 2023
Background Infective endocarditis of the aortic valve is a relatively common disease presentation, with surgical intervention a mainstay of treatment in severe cases.
Ariana M. Goodman   +4 more
doaj   +1 more source

Surgical Explantation of Transcatheter Aortic Valve Bioprostheses [PDF]

open access: bronze, 2021
Alexander A. Brescia   +11 more
openalex   +1 more source

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