Results 241 to 250 of about 5,255,725 (300)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Precision RNA interference of Smad3 and Runx2 via dual targeting nanocarriers mitigates aortic valve disease. [PDF]

J Transl Med
Voicu G, Mocanu CA, Safciuc F, Anghelache M, Turtoi M, Deleanu M, Simionescu M, Manduteanu I, Calin M.   +8 more
europepmc   +1 more source

A case report of sanguisis streptococcal sepsis associated with the orthodontic appliance in a young male with aortic valve disease. [PDF]

Open Med (Wars)
Al Hariri B, Hassan YA, Mohamed A, Hassan MA.   +3 more
europepmc   +1 more source

Extracellular Vesicles in Calcific Aortic Valve Disease: From Biomarkers to Drug Delivery Applications. [PDF]

Biomolecules
Cook-Calvete A, Delgado-Marin M, Fernandez-Rodriguez B, Zaragoza C, Saura M.   +4 more
europepmc   +1 more source

Corrigendum to "Extracellular matrix remodeling in calcific aortic valve disease: Localized enrichment of type III collagen and LTBP-4" [Matrix Biol Plus 30 (2026) 100194]. [PDF]

Matrix Biol Plus
Kemmochi R, Miyazaki H, Taga Y, Takahashi N, Watanabe T, Ikemura K, Sasaki T, Mizuno K, Hirohata S, Matsumoto M, Oohashi T.   +10 more
europepmc   +1 more source

Dysglycaemia and the risk of incident aortic valve disease: A population-based cohort study. [PDF]

Medicine (Baltimore)
Arain LN, Khan A, Parveen A, Malik J.
europepmc   +1 more source

Unicuspid Aortic Valve Disease: The Role of Imaging in Diagnosis and Timely Surgical Planning. [PDF]

Cureus
Gupta M, Kodamanchile A, Zafeiri M, Venkatraghavan P, Cole A.   +4 more
europepmc   +1 more source

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Genetics of aortic valve disease

Current Opinion in Cardiology, 2023
Purpose of review Aortic valve disease is a leading global cause of morbidity and mortality, posing an increasing burden on society. Advances in next-generation technologies and disease models over the last decade have further delineated the genetic and molecular factors that might be exploited in development of therapeutics ...
Ruth L, Ackah, Jun, Yasuhara, Vidu, Garg
openaire   +2 more sources

Dyslipidemia and aortic valve disease

Current Opinion in Lipidology, 2021
Purpose of review Degenerative aortic stenosis (AS) is one of the most prevalent heart valve diseases in the adult population. The understanding of AS pathophysiology and involved risk factors have recently undergone a great advance, with low-density lipoprotein cholesterol (LDL-C), lipoprotein (a) [Lp(a)] and other clinical ...
Pedro, Mata, Rodrigo, Alonso, Leopoldo, Pérez de Isla, Lina, Badimón   +3 more
openaire   +2 more sources