Results 101 to 110 of about 49,045 (265)

Prosthetic Repair of the Ascending Aorta in a Patient with Aortic Dissection Type A after Coronary Artery Bypass Grafting (Case Report)

Український журнал серцево-судинної хірургії, 2019
Aortic dissection after cardiac surgery is a rare abnormality in patients after prior coronary artery bypass grafting. This abnormality is often accompanied by aortic valve insufficiency, lower extremity malperfusion syndrome and other symptoms.
A. V. Pavlenko, S. V. Varbanets, O. M. Dovgan, O. Y. Pukas   +3 more
doaj   +1 more source

Response to equine cardiac adverse events during sports

Equine Veterinary Education, EarlyView.
Summary Cardiac adverse events and sudden death are a feared scenario for equine veterinarians, with serious consequences for animal health, riders' safety and the social licence to operate equestrian sports. The response to equine cardiac adverse events (CAEs) during sports is poorly defined.
C. Navas de Solis, J. Keen, A. Decloedt, B. Delvescovo, K. Hopster, K. Mitchell, J. Slack, G. van Loon, G. Van Steenkiste, L. Nath   +9 more
wiley   +1 more source

Quadricuspid aortic valve by using intraoperative transesophageal echocardiography

Cardiovascular Ultrasound, 2010
Quadricuspid aortic valve is a rare congenital malformation of the aortic valve. Its diagnosis is often missed even with the use of transthoracic echocardiogram.
Xiao Zhenghua, Meng Wei, Zhang Eryong
doaj   +1 more source

Balloon valvuloplasty of aortic valve stenosis in childhood: early and medium term results [PDF]

, 2018
Background: Isolated aortic valve stenosis in childhood is treated by balloon valvuloplasty. The role of independent risk factors for the outcome remains unclear.
Berger, Felix, Harpes, Paul, Knirsch, Walter, Kretschmar, Oliver   +3 more
core  

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Tricuspid valve dysplasia in dogs [PDF]

, 2018
A general overview of tricuspid valve dysplasia in dogs is presented in this review. This congenital disease has been described in numerous large dog breeds but especially the Labrador retriever is predisposed.
Bavegems, Valérie, Broeckx, Bart, De Rooster, Hilde, Favril, Sophie, Peelman, Luc, Smets, Pascale   +5 more
core   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Type F congenital quadricuspid aortic valve: A very rare case diagnosed by 3-dimenional transoesophageal echocardiography [PDF]

, 2014
Congenital quadricuspid aortic valve (QAV) is a rare cardiac anomaly. Several different anatomical variations of a quadricuspid aortic valve have been described.
Cooke JC, Davia JE, Di Pino A, Feldman BJ, Fernández B, Gulyasy B, Hazlyna Kamaruddin, Holt NF, Hurwitz LE, Olson LJ, Pankaj Garg, Rachel Orme, Scrofani R, Takeda N, Tang YF, Tutarel O, Victoria Watt, Ward C   +17 more
core   +2 more sources

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source