Results 101 to 110 of about 34,832 (247)

Bicuspid Aortic Valve Disease and Ascending Aortic Aneurysms: Gaps in Knowledge

Cardiology Research and Practice, 2012
The bicuspid aortic valve is the most common congenital cardiac anomaly in developed nations. The abnormal bicuspid morphology of the aortic valve results in valvular dysfunction and subsequent hemodynamic derangements. However, the clinical presentation
Katie L. Losenno, Robert L. Goodman, Michael W. A. Chu   +2 more
doaj   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Perioperative Outcomes in Factor XI Deficiency: A Systematic Review

Haemophilia, EarlyView.
ABSTRACT Background Congenital factor XI (FXI) deficiency has a variable bleeding phenotype, and FXI activity alone does not predict perioperative bleeding. Management practices remain heterogeneous, and available evidence derives from case reports, small case series, and retrospective cohorts.
Zainab Al‐Housni, Raeesah Mohammed, Silvio Ligia, Jim Douketis, Chatree Chai‐Adisaksopha, Alfonso Iorio, Davide Matino   +6 more
wiley   +1 more source

The V6R/V4R Index: A Novel ECG Parameter for Identifying Idiopathic Ventricular Arrhythmias Originating From the Aortic Cusp

Journal of Cardiovascular Electrophysiology, EarlyView.
The V6R/V4R amplitude index is a novel and practical electrocardiographic parameter for identifying idiopathic ventricular arrhythmias originating from the aortic cusp. A cutoff >0.55 accurately distinguishes cusp from adjacent non‐cusp origins within the left ventricular outflow tract, facilitating targeted mapping and procedural planning.
Yoshihisa Naruse, Kohki Nakamura, Kanae Hasegawa, Toshihiko Tsuji, Machiko Miyoshi, Tatsuhiro Kataoka, Hideyuki Aoki, Yoshinori Okazaki, Shigeto Naito, Hiroshi Tada, and other members of the V6R/V4R Study Group, Tomoki Kaeriyama, Shigeki Horiguchi, Kaori Hisazaki, Takehito Sasaki, Kentaro Minami, Yutaro Kaneko, Taro Narumi, Makoto Sano, Yuichiro Maekawa   +19 more
wiley   +1 more source

Standardized Reporting of Cardiac Magnetic Resonance Examinations in Children With Cardiac Diseases and Adults With Congenital Heart Disease: A Scientific Statement From the Association for European Pediatric and Congenital Cardiology (AEPC) and the International Society for Magnetic Resonance in Medicine (ISMRM)

Journal of Magnetic Resonance Imaging, EarlyView.
Francesca Raimondi, Inga Voges, Lamia Ait‐Ali, Sonya Babu‐Narayan, Rene Botnar, Barbara Burkhardt, Adrienne Campbell‐Washburn, Dominik Daniel Gabbert, Georg Hansmann, Willem A. Helbing, Hasan Hosan, Sylvia Krupickova, Heiner Latus, Duarte Martins, Colin McMahon, Christian Meierhofer, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Claudia Prieto, Milan Prsa, Kuberan Pushparajah, José F. Rodríguez Palomares, Samir Sarikouch, Lars Grosse‐Wortman, F. Gerald Greil, Heynric Grotenhuis   +26 more
wiley   +1 more source

Dynamic Behavior of Left Atrial Low‐Voltage Areas in Persistent Atrial Fibrillation: Implications for Substrate‐Guided Ablation

Journal of Cardiovascular Electrophysiology, EarlyView.
Patient selection and analysis flow diagram. The exact pre‐inclusion denominator and reliable reason‐specific exclusion counts could not be reconstructed because a prospectively maintained screening log was unavailable. The diagram summarizes the final study cohort and analysis‐specific sample sizes. AF, atrial fibrillation; LVA, low‐voltage area; SR1,
Yunus Emre Özbebek, Özcan Özdemir, Sinan Boz, Haluk Furkan Şahan, Engin Algül, Sinan İşcen, Hamza Sunman, Tolga Han Efe   +7 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Severe aortic valve insufficiency with a 'normal' appearing aortic root: reimplantation (David) procedure. [PDF]

Ann Cardiothorac Surg, 2023
Boodhwani M, Guo MH, Dryden A, Glineur D.   +3 more
europepmc   +1 more source

Pre‐anaesthetic risk assessment and management of dogs with myxomatous mitral valve disease: a spectrum of care narrative review

Journal of Small Animal Practice, EarlyView.
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon, L. Köster, E. Vettorato, A. H. Estrada   +3 more
wiley   +1 more source