Results 71 to 80 of about 176,564 (365)

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome [PDF]

, 2008
Background: Progressive enlargement of the aortic root, leading to dissection, is the main cause of premature death in patients with Marfan's syndrome. Recent data from mouse models of Marfan's syndrome suggest that aortic-root enlargement is caused by ...
Brooke, Benjamin S., Dietz, Harry C., Habashi, Jennifer P., Judge, Daniel P., Loeys, Bart, Patel, Nishant   +5 more
core   +2 more sources

Emergency Valve-in-Valve Transcatheter Aortic Valve Implantation for the Treatment of Acute Stentless Bioprosthetic Aortic Insufficiency and Cardiogenic Shock

Case Reports in Cardiology, 2018
Bioprosthetic aortic valve degeneration may present as acute, severe aortic regurgitation and cardiogenic shock. Such patients may be unsuitable for emergency valve replacement surgery due to excessive risk of operative mortality but could be treatable ...
Ivan D. Hanson, Pratik K. Dalal, Brian M. Renard, George S. Hanzel, Alessandro Vivacqua   +4 more
doaj   +1 more source

Isolated aortic insufficiency valve repair with external ring annuloplasty: a standardized approach.

European Journal of Cardio-Thoracic Surgery, 2019
OBJECTIVES Aortic valve (AV) insufficiency with normal root and ascending aorta is most frequently treated by valve replacement with significant prosthetic-related complications and reduced life expectancy.
M. Zakkar, V. Bruno, P. Zacek, I. Di Centa, C. Acar, N. Khelil, M. Debauchez, E. Lansac   +7 more
semanticscholar   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Brucella endocarditis of the aortic valve [PDF]

, 1998
Brucella endocarditis was diagnosed in two patients with acute renal failure. Both patients had major aortic insufficiency, congestive cardiac failure and clinical and laboratory signs of an active infection, although adequate antibacterial therapy had ...
Antunes, MJ, Leandro, J, Roberto, H
core   +1 more source

Delayed traumatic aortic valve perforation after blunt chest trauma

Surgical Case Reports
Background Aortic valve perforation is a rare complication of blunt chest trauma. We report a case of delayed aortic insufficiency presenting several months after trauma.
Kazuki Noda, Yosuke Takahashi, Akimasa Morisaki, Yoshito Sakon, Kenta Nishiya, Goki Inno, Yukihiro Nishimoto, Yosuke Sumii, Munehide Nagao, Toshihiko Shibata   +9 more
doaj   +1 more source

Degenerative changes of the aortic valve during left ventricular assist device support

ESC Heart Failure, 2022
Aims Donor heart shortage leads to increasing use of left ventricular assist device (LVAD) as bridge‐to‐transplant or destination therapy. Prolonged LVAD support is associated with aortic valve insufficiency, representing a relevant clinical problem in ...
Mareike Barth, Linus Mrozek, Naima Niazy, Jessica Isabel Selig, Udo Boeken, Yukiharu Sugimura, Nikolaos Kalampokas, Patrick Horn, Ralf Westenfeld, Patric Kröpil, Hug Aubin, Artur Lichtenberg, Payam Akhyari   +12 more
doaj   +1 more source

Survival and repair durability in patients undergoing concomitant aortic valve reimplantation and mitral valve repairCentral MessagePerspective

JTCVS Techniques, 2023
Objective: The study objective was to determine repair durability and survival in patients with and without connective tissue disorders undergoing concomitant aortic valve reimplantation and mitral valve repair.
Daniel J.P. Burns, MD, MPhil, Jeevanantham Rajeswaran, PhD, Milind Y. Desai, MD, A. Marc Gillinov, MD, Kevin Hodges, MD, Eric E. Roselli, MD, Patrick R. Vargo, MD, Lars G. Svensson, MD, PhD   +7 more
doaj   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Transcatheter Aortic Valve Replacement for Bicuspid Aortic Insufficiency After Valve-Sparing Aortic Root Replacement

JACC: Case Reports, 2021
Bicuspid aortic insufficiency (BAI) patients with root aneurysm often require aortic valve and root replacement in a composite procedure. The valve-sparing root replacement (VSARR) procedure is aimed at preserving the native valve when possible.
Ofir Koren, Vivek Patel, Danon Kaewkes, Keita Koseki, Tarun Chakravarty, Mamoo Nakamura, Cheng Wen, Robert Naami, Raj R. Makkar   +8 more
openaire   +2 more sources