Results 51 to 60 of about 916,946 (302)

Cost-utility of transcatheter aortic valve implantation for inoperable patients with severe aortic stenosis treated by medical management: a UK cost-utility analysis based on patient-level data from the ADVANCE study. [PDF]

, 2014
OBJECTIVE: To use patient-level data from the ADVANCE study to evaluate the cost-effectiveness of transcatheter aortic valve implantation (TAVI) compared to medical management (MM) in patients with severe aortic stenosis from the perspective of the UK ...
Busca, R, Axel Linke, Amie Padhiar, Peter Wenaweser, Neil Moat, Piazza, N, Stuart Mealing, Johan Bosmans, Mealing, S, Stephen Brecker, Mark Sculpher, Ulrich J Gerckens, Nicolo Piazza, Rachele Busca, Padhiar, A, Sabine Bleiziffer, Tamburino, C, Sculpher, M, Bosmans, J, Gerckens, UJ, Bleiziffer, S, Linke, A, James Eaton, Eaton, J, Wenaweser, P, Moat, N, Corrado Tamburino, Brecker, S, Brecker, Stephen, Mealing, Stuart, Padhiar, Arnie, et al., Bosmans, Johan   +32 more
core   +1 more source

Data_Sheet_1_Integrated Aortic-Valve-And-Ascending-Aortic Replacement vs. Partial Replacement in Bicuspid Aortic Valve-Related Aortopathy.docx

, 2021
Objective: We sought to evaluate the outcomes of integrated aortic-valve and ascending-aortic replacement (IR) vs. partial replacement (PR) in patients with bicuspid aortic valve (BAV)-related aortopathy.Methods: We compared long-term mortality ...
Yan Ding (39795), Yongmin Liu (1751752), Wei Zhang (405), Weimin Li (131040), Honglei Zhao (330799), Lizhong Sun (714497), Mi Chen (32731), Wangli Xu (4741278), Chenyang Zhou (846324), Junnan Jia (9187289), Junming Zhu (448145), Bo Yang (104813), Pei Wang (102036), Tao Bai (90717), Jinrong Xue (11865986), Huanyu Qiao (155042)   +15 more
core   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Non-linear finite element analyses of the aortic heart valve [PDF]

, 2004
Includes bibliographical references.Finite element models of the aortic heart valve have been successfully used in the past to gain insight into the mechanics of the valve and to aid in understanding of valve failure.
Koch, Thorsten M
core   +1 more source

Durability of Soft Pneumatic Actuators: A Review and Benchmarking Protocol

Advanced Robotics Research, EarlyView.
Lack of durability is a key challenge hindering the broad scale adoption of soft pneumatic actuators (SPAs) in automation industries. This review provides a comprehensive overview of existing research on SPA durability, introduces a standardized durability benchmarking protocol to consolidate the testing of SPAs, and outlines promising directions for ...
Dickson Chiu Yu Wong, Yucheng Luo, Rob Bernardus Nicolaas Scharff   +2 more
wiley   +1 more source

Stentless aortic valve replacement: an update [PDF]

, 2011
Junjiro KobayashiDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, JapanAbstract: Although porcine aortic valves or pericardial tissue mounted on a stent have made implantation techniques easier, these valves ...
Kobayashi J, Junjiro Kobayashi
core   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Awake Surgical Mitral Valve Repair after Transcatheter Aortic Valve Replacement

The Thoracic & Cardiovascular Surgeon Reports, 2021
Transcatheter aortic valve replacement has become a popular choice for cases with severe aortic stenosis. However, when severe mitral regurgitation is comorbid in high-risk patients with severe aortic stenosis, therapeutic options must be weighed for ...
Aina Hirofuji, Hirotsugu Kanda, Yuya Kitani, Hiroyuki Kamiya   +3 more
doaj   +1 more source

First Transapical Aortic Valve Replacement at Bagcilar Training and Research Hospital [PDF]

, 2016
Transcatheter-based aortic valve procedures have undergone a tremendous evolution and have led to great changes in the treatment of aortic valvular disease.
Kamil Boyacioglu, Ibrahim Yildizhan, Nihan Kayalar, Serkan Ketenciler, Vedat Erentug   +4 more
core   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source