Results 151 to 160 of about 245,053 (402)

Safety and Efficacy of a Plug‐Based Vascular Closure Device After Percutaneous Microaxial Flow Pump in the Treatment of Complex and High‐Risk Indicated Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Femoral large‐bore vascular access is an important and constantly increasing technique in interventional treatment. Temporary circulatory support in complex and high‐risk indicated patients (CHIP) presents a challenge in terms of postinterventional access site closure.
Jörg W. Schröder, Norman Mangner, Felix J. Woitek, Kai U. Markus, Michael Lehrke, Felix Vogt, Marlo Verket, Alexandros Siskos, Moritz Biener, Benjamin Meder, Nicolas M. Van Mieghem   +10 more
wiley   +1 more source

Genome-wide analysis yields new loci associating with aortic valve stenosis

bioRxiv, 2017
Aortic valve stenosis (AS) is the most common valvular heart disease, and valve replacement is the only definitive treatment. Here we report a large genome-wide association (GWA) study of 2,457 Icelandic AS cases and 349,342 controls with a follow-up in ...
A. Helgadóttir, G. Thorleifsson, S. Gretarsdottir, Olafur A. Stefansson, V. Tragante, Rosa B. Thorolfsdottir, I. Jónsdóttir, I. Jónsdóttir, Thorsteinn Bjornsson, V. Steinthorsdottir, N. Verweij, N. Verweij, J. Nielsen, Wei Zhou, L. Folkersen, L. Folkersen, A. Martinsson, M. Heydarpour, Siddharth K. Prakash, G. Óskarsson, T. Gudbjartsson, A. Geirsson, I. Olafsson, E. Sigurdsson, P. Almgren, O. Melander, A. Franco-Cereceda, A. Hamsten, L. Fritsche, Maoxuan Lin, Bo Yang, W. Hornsby, D. Guo, C. Brummett, G. Abecasis, M. Mathis, D. Milewicz, D. Milewicz, S. Body, P. Eriksson, C. Willer, K. Hveem, C. Newton‐Cheh, C. Newton‐Cheh, J. Smith, R. Danielsen, G. Thorgeirsson, G. Thorgeirsson, U. Thorsteinsdóttir, U. Thorsteinsdóttir, D. Gudbjartsson, D. Gudbjartsson, H. Hólm, K. Stefánsson, K. Stefánsson   +54 more
semanticscholar   +1 more source

Impact of Elevated Preprocedural Left Ventricular Filling Pressure on Prognosis of Mild Paravalvular Regurgitation Following Transcatheter Aortic Valve Replacement

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Paravalvular regurgitation (PVR) following transcatheter aortic valve replacement (TAVR) is a complication linked to poor outcomes. The prognostic impact of mild PVR, particularly in patients with elevated preprocedural left ventricular (LV) filling pressure, remains uncertain.
Shumpei Kosugi, Isamu Mizote, Daisuke Nakamura, Hiroki Sugae, Yutaka Matsuhiro, Shota Okuno, Ai Kawamura, Kizuku Yamashita, Koichi Maeda, Kazuo Shimamura, Tomoharu Dohi, Yasuharu Takeda, Yasushi Sakata   +12 more
wiley   +1 more source

Low-Gradient, Low Ejection Fraction Severe Aortic Stenosis: Still a Management Conundrum

Cardiovascular Innovations and Applications, 2018
The management of patients with severe symptomatic aortic stenosis and a high transvalvular gradient is straightforward. It requires aortic valve replacement. Management of aortic stenosis patients with low flow, low ejection fraction and low gradient is
Blase A. Carabello
doaj   +1 more source

Aortic Stenosis Poster [PDF]

, 2019
Aortic stenosis is the narrowing of the aortic valve secondary to calcification and fibrosis. It is the most common valve disorder and the second most frequent reason for cardiac surgery.
Lawson, Katonya
core   +1 more source

Transcatheter Aortic Valve Implantation in Patients with Bicuspid Aortic Valve Stenosis

Heart, Lung and Circulation, 2010
We evaluated transcatheter aortic valve implantation (TAVI) in high-risk patients with bicuspid aortic valve (BAV) stenosis.TAVI shows promise in the treatment of severe stenosis of triscupid aortic valves, especially in high-risk patients. However, BAV stenosis has been considered a contraindication to TAVI.Eleven patients (age 52 to 90 years) with ...
David A. Wood, Josep Rodés-Cabau, Anson Cheung, Jian Ye, Madhu K. Natarajan, Namal Wijesinghe, Eric Dumont, James L. Velianou, Edgar Tay, Ronen Gurvitch, John G. Webb, Fabian Nietlispach   +11 more
openaire   +4 more sources

OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA–NF-&kgr;B pathway

Cardiovascular Research, 2017
Aims Oxidatively modified lipoproteins may promote the development/progression of calcific aortic valve stenosis (CAVS). Oxidative transformation of low-density lipoprotein (OxLDL) generates lysophosphatidic acid (LPA), a lipid mediator that accumulates ...
M. J. Nsaibia, Marie-Chloé Boulanger, R. Bouchareb, G. Mkannez, Khai Le Quang, F. Hadji, Deborah Argaud, A. Dahou, Y. Bossé, M. Koschinsky, P. Pibarot, B. Arsenault, A. Marette, P. Mathieu   +13 more
semanticscholar   +1 more source

Overlap of Takayasu Arteritis and Kawasaki Disease in Infants

Chronic Diseases and Translational Medicine, EarlyView.
Echocardiography showed the myocardial ischemia presentation of an 8‐month‐old boy.
Jingya Li, Yan Sun, Liyuan Xu, Shanshan Li, Ning Ma   +4 more
wiley   +1 more source

Transcatheter Aortic‐Valve Replacement with a Balloon‐Expandable Valve in Low‐Risk Patients

New England Journal of Medicine, 2019
BACKGROUND Among patients with aortic stenosis who are at intermediate or high risk for death with surgery, major outcomes are similar with transcatheter aortic‐valve replacement (TAVR) and surgical aortic‐valve replacement.
M. Mack, M. Leon, V. Thourani, R. Makkar, S. Kodali, M. Russo, S. Kapadia, C. Malaisrie, D. Cohen, P. Pibarot, J. Leipsic, R. Hahn, P. Blanke, Mathew R. Williams, J. McCabe, David L. Brown, V. Babaliaros, S. Goldman, W. Szeto, P. Généreux, A. Pershad, S. Pocock, Maria C. Alu, J. Webb, Craig R. Smith   +24 more
semanticscholar   +1 more source

PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis.

Journal of Clinical Endocrinology and Metabolism, 2016
CONTEXT Novel, low-density lipoprotein (LDL) cholesterol-lowering proprotein convertase subtilisin/kexin type-9 (PCSK9) inhibitors also lower lipoprotein(a) levels, but the effect on aortic valve stenosis and myocardial infarction is unknown ...
A. Langsted, B. Nordestgaard, M. Benn, A. Tybjærg‐Hansen, P. Kamstrup   +4 more
semanticscholar   +1 more source