Results 221 to 230 of about 269,298 (386)
Secukinumab in the Treatment of Moderate‐to‐Severe Hidradenitis Suppurativa: Pooled Pharmacokinetics and Safety Results From the SUNSHINE and SUNRISE Phase 3 Studies
International Journal of Dermatology, EarlyView.ABSTRACT Background
Secukinumab, a fully human, monoclonal antibody targeting interleukin‐17A, is approved for moderate‐to‐severe HS in adults. This study evaluated pharmacokinetics (PK), high‐sensitivity C‐reactive protein (hsCRP) changes, and safety of secukinumab over 52 weeks in SUNSHINE and SUNRISE Phase 3 trials.Afsaneh Alavi, Ziad Reguiai, Gregor B. E. Jemec, Alice B. Gottlieb, Magdalena B. Wozniak, Lorenz Uhlmann, Heng Fan, Angela Llobet Martinez, Gerard Bruin, Nicolas Thomas, Ivette Alarcon, Bruno Bieth, Shoba Ravichandran, Alexa B. Kimball +13 morewiley +1 more sourceSelf-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery [PDF]
, 2014 Michael J. Reardon, David Adams, Joseph S. Coselli, G. Michael Deeb, Neal S. Kleiman, Stan Chetcuti, Steven J. Yakubov, David Heimansohn, James Hermiller, G. Chad Hughes, J. Kevin Harrison, Kamal R. Khabbaz, Peter Tadros, George L. Zorn, William Merhi, John Heiser, George Petrossian, N. Bryce Robinson, Brijeshwar Maini, Mubashir Mumtaz, Joon Sup Lee, Thomas G. Gleason, Jon R. Resar, John V. Conte, Daniel Watson, Sharla Chenoweth, Jeffrey J. Popma +26 moreopenalex +1 more sourceStaging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis.
Journal of the American College of Cardiology, 2019 L. Tastet, C. Tribouilloy, S. Maréchaux, E. M. Vollema, V. Delgado, E. Salaun, Mylène Shen, R. Capoulade, M. Clavel, M. Arsenault, É. Bédard, M. Bernier, J. Beaudoin, J. Narula, P. Lancellotti, Jeroen J. Bax, P. Généreux, P. Pibarot +17 moresemanticscholar +1 more sourceEfficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial
Journal of the American Geriatrics Society, EarlyView.Clinical management of the older adult. ABSTRACT Objectives
Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design
Multicenter cluster randomized clinical trial.Adriana Abizanda Saro, Rafael García Molina, Rubén Alcantud Córcoles, Manuel Maestre Moreno, Raúl Sánchez Uceda, Ignacio Morón Merchante, Antonio Aragonés Jiménez, María Dolores González Céspedes, Pilar Montero Alía, Marta Simarro Rueda, Luis Torres Antón, Pilar Martínez García, Humberto Soriano Fernández, Marta Córcoles García, Ángel Moises Reyes Abreu, María Nuria Morcillo González, Elena García Páez, Beatriz Rodríguez Sánchez, Marta Sáez Blesa, Elisa Belén Cortés Zamora, Fernando Andrés Pretel, Almudena Avendaño Céspedes, FRAILMERIT Study Group, Aránzazu Rodríguez Ortiz, Raquel González Herreros, José Luis Carboneras Atienza, Lisbeth Rodríguez Gómez, Hugo García López, Clotilde Boix Gras, Lorena Moreno Hernández, Jesús López‐Torres Hidalgo, Maximiliano Martínez Ramírez, Francisco Escobar Rabadán, Juan Manuel Téllez Lapeira, Esther Limón Romero, Clara Soler Gimbernat, Laura Grimal Abejez, Mercé Jioménez González, Verónica Griselda Echenique Portillo, Alexandre Ortega Roca, Meritxell Carmona Cervelló, Carla Chacón Valera, Carmen Rodríguez Buza, Óscar Cobos Cano, María Julia Sánchez Maestre, Ana Fons Diaz, Javier Ibáñez Rivas, Marina Carmona García, Inmaculada Sag Lesmes, Alfredo Ortiz Arjona, Alejandro Becerra Serrano, Antonia Prieto Cuesta, Ana Sánchez Maestre, Carlos Eusebio Esparza Ferrera, Miriam Bueno León, Cristina Figueroa Martín, Noelia Díaz Hernández, Patricia Gutiérrez González, Quintina Pérez Quesada, Soraya Sotto Rodríguez, Guacimara Delgado Jiménez, María Florentina Álvarez Álvarez, Yudanis Sánchez Alpízar, Diego Aparicio Barrilero, Paloma de Teodoro Idiago, Sandra Benito Prieto, Ana Pilar Javierre Miranda, Elena Mendoza Fernández, Emma Camino Ortega, Ana de Baroja Gil deGómez, María Lafuente Yanguas, Antía Codina Rodríguez, Amelia González Gamarra, José Gutiérrez Rodríguez, José Miguel Arche Coto, Eva López Alvarez, Alvaro Revuelta Argomaniz, Cristina Alonso Bouzón, José Antonio Serra Rexach, Jennifer Mayordomo Cava, Marta Carolina Ruiz Grao, Luis Aguilar Salmerón, Alicia Noguerón García, Elena Martín Sebastiá, Elena Gómez Jiménez, Cristina Gómez Ballesteros, Pedro Abizanda +86 morewiley +1 more sourceAortic valve stenosis and osteoporosis: insights from a mouse model. [PDF]
BMC Cardiovasc DisordBillig H, Schmitt J, Singer L, Bourauel C, Schildberg FA, Masson W, Lübbering N, Vogel W, Perner S, Stei M, Niepmann S, Silaschi M, Bakhtiary F, Nickenig G, Zimmer S. +14 moreeuropepmc +1 more sourceActivated platelets promote an osteogenic programme and the progression of calcific aortic valve stenosis
European Heart Journal, 2019 R. Bouchareb, Marie-Chloé Boulanger, L. Tastet, G. Mkannez, M. J. Nsaibia, F. Hadji, A. Dahou, Y. Messadeq, B. Arsenault, P. Pibarot, Y. Bossé, A. Marette, P. Mathieu +12 moresemanticscholar +1 more source