Results 231 to 240 of about 118,216 (311)

Conjugated bile acids are elevated in severe calcific aortic valve stenosis. [PDF]

J Lipid Res
Zhang H, Atefi N, Surendran A, Han J, Goodlett DR, Jassal DS, Shah A, Ravandi A.   +7 more
europepmc   +1 more source

Redefining Frailty: Planning Care Through the Frailty Trajectory Model

Journal of the American Geriatrics Society, EarlyView.
Figure 1. The frailty cycle begins when an individual is already frail and thus vulnerable to decline, designated as baseline frailty. An acute health event or medical intervention initiates the cycle. Despite usual care, there is deterioration in cognition, function, mobility, and/or symptoms, resulting in incomplete recovery.
Laurie Mallery, Nabha Shetty
wiley   +1 more source

Valvular Endothelial Cell Heterogeneity Reflects Different Pathogenesis of Tricuspid and Bicuspid Aortic Valve Stenosis in Humans. [PDF]

J Am Heart Assoc
Brandtner A, Brückner A, Röll W, Bakhtiary F, Fleischmann BK, Wenzel D.   +5 more
europepmc   +1 more source

Prevalence and Impact of Atrial Fibrillation in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

, 2016
Giuseppe Tarantini, Marco Mojoli, Stephan Windecker, Olaf Wendler, Thierry Lefèvre, Francesco Saia, Thomas Walther, Paolo Rubino, Antonio L. Bartorelli, Massimo Napodano, Augusto D’Onofrio, Gino Gerosa, Sabino Iliceto, Alec Vahanian   +13 more
openalex   +2 more sources

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Inflammation and Adipocyte Metabolism in Calcific Aortic Valve Stenosis: When New Is Well-Forgotten Old. [PDF]

JACC Basic Transl Sci
Malashicheva A.
europepmc   +1 more source

The JAK2V617F and CALR mutations and risk of cancer, cardiovascular diseases, and all‐cause mortality

Journal of Internal Medicine, EarlyView.
Abstract Background Clonal hematopoiesis (CH) is associated with adverse outcomes. We hypothesized that CH (JAK2V617F and CALR) is associated with cancer, vascular disease, and all‐cause mortality, even at a variant allele frequency (VAF) <1%. Methods We screened 19,832 individuals from the Danish General Suburban Population Study for JAK2V617F and ...
Morten Kranker Larsen, Vibe Skov, Lasse Kjær, Christina Schjellerup Eickhardt‐Dalbøge, Trine Alma Knudsen, Marie Hvelplund Kristiansen, Anders Lindholm Sørensen, Sabrina Cordua, Troels Wienecke, Mette Grymer Jensen, Morten Andersen, Johnny T. Ottesen, Johanne Gudmand‐Høyer, Jordan Andrew Snyder, Henrik Enghusen Poulsen, Thomas Stiehl, Christina Ellervik, Hans Carl Hasselbalch   +17 more
wiley   +1 more source

Bibliometric analysis of treatment modalities in calcific aortic valve stenosis. [PDF]

Front Pharmacol
He Y, Yang YJ, Wang ZJ, Tang L.
europepmc   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Physical frailty, genetic predisposition, and risk of incident degenerative aortic valve stenosis: A prospective cohort study. [PDF]

J Nutr Health Aging
Su B, Zhu P, Chen C, Su Z, Shen T.
europepmc   +1 more source