Results 271 to 280 of about 118,216 (311)

Zero Fluoroscopy Ablation of Arrhythmias in Patients With Congenital Heart Disease

Journal of Arrhythmia, Volume 41, Issue 6, December 2025.
Zero‐fluoroscopy radiofrequency ablation using 3D electroanatomic mapping was performed in 42 patients with mild, moderate, or great complexity congenital heart disease. Acute success was 100%, with no complications and minimal recurrence over 48 months. This approach eliminates radiation exposure while maintaining safety and efficacy across select yet
Shailendra Upadhyay, Jenna Schermerhorn, Whitney Fairchild, Jamie Bopp, Irfan Warsy   +4 more
wiley   +1 more source

Trpv4-mediated mechanotransduction regulates the differentiation of valvular interstitial cells to myofibroblasts: implications for aortic valve stenosis. [PDF]

Am J Physiol Cell Physiol
Mukherjee P, Mahanty M, Dutta B, Rahaman SG, Sankaran KR, Liu Z, Rahaman SO.   +6 more
europepmc   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, Volume 14, Issue 28, November 3, 2025.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Transcriptomic Signatures of Calcific Aortic Valve Stenosis Severity in Human Tricuspid and Bicuspid Aortic Valves. [PDF]

JACC Basic Transl Sci
Houessou U, Zamani P, Manikpurage HD, Li Z, Gaudreault N, Dahmene M, Dagenais F, Couture C, Clavel MA, Pibarot P, Mathieu P, Bossé Y, Thériault S.   +12 more
europepmc   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Diagnostic Challenges in the Management of Aortic Valve Stenosis and the Role of Imaging: A Narrative Review. [PDF]

J Clin Med
Karelas D, Tatsis E, Oikonomidis D, Papadopoulos CH.   +3 more
europepmc   +1 more source

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear, Paul Kalitsis, Melissa Glass, Bertrand Isidor, Catherine Vincent‐Delorme, Florence Petit, Judith M. A. Verhagen, Alexander Jorge, Ana Cristina Victorino Krepischi, Ikeoluwa Osei‐Owusu, Eva Martinez, Anne O'Donnell‐Luria, Nicole de Leeuw, Sarah Ruggiero, Ingo Helbig, Francis David I, Natasha J. Brown   +16 more
wiley   +1 more source

Transcatheter Aortic Valve Replacement for a Severe Aortic Valve Stenosis Coexisting with Hypertrophic Obstructive Cardiomyopathy - A Tale of Two Obstructions. [PDF]

Acta Cardiol Sin
Lin YS, Yu CL, Lee WL, Lin WW, Liang KW.
europepmc   +1 more source

Maternal Sirolimus Treatment Reverses Cardiac Rhabdomyoma‐Induced Hydrops Fetalis in a Twin Gestation With Tuberous Sclerosis Complex

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Cardiac rhabdomyomas are often the presenting sign of tuberous sclerosis complex (TSC). Prior reports have shown that maternal sirolimus treatment can reduce rhabdomyomas. We used maternal sirolimus to reverse hydrops fetalis due to a massive cardiac rhabdomyoma in a twin gestation.
David M. Ritter, Kristin Schneider, Nkiru Ezeakudo, Darcy A. Krueger, Tomoyuki Mizuno, Timothy K. Knilans, David N. Franz   +6 more
wiley   +1 more source