Transcatheter Aortic Valve Therapy for Bicuspid Aortic Valve Stenosis
Transcatheter aortic valve implantation (TAVI) has become first-line treatment for older adults with severe aortic stenosis (AS), however, patients with bicuspid aortic valve (BAV) have been traditionally excluded from randomised trials and guidelines.
Nalin H. Dayawansa+3 more
openaire +3 more sources
Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterolemic mice. [PDF]
There are no rigorously confirmed effective medical therapies for calcific aortic stenosis. Hypercholesterolemic Ldlr (-/-) Apob (100/100) mice develop calcific aortic stenosis and valvular cardiomyopathy in old age.
Robert M Weiss+9 more
doaj +1 more source
Aortic valve stenosis is the most frequent valve disease in developed countries and its prevalence will increase with population aging. There is still no pharmaceutical treatment nor biomarker to determine the susceptibility to develop aortic stenosis ...
Alejandro Junco-Vicente+10 more
doaj +1 more source
Interdisciplinary three-step strategy to treat aortic stenosis and coronary artery disease in a patient with end-stage chronic obstructive pulmonary disease [PDF]
Background: Valvular aortic stenosis is a common disease in the elderly, often in multimorbid patients. It is often associated with coronary artery disease and peripheral artery disease.
Beiras Fernández, Andrés+6 more
core +2 more sources
Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Stenosis
After 15 years of successive randomized, controlled trials, indications for transcatheter aortic valve replacement (TAVR) are rapidly expanding. In the coming years, this procedure could become the first line treatment for patients with a symptomatic severe aortic stenosis and a tricuspid aortic valve anatomy.
Vincent, Flavien+16 more
openaire +3 more sources
Transcatheter Aortic Valve Implantation in Dialysis Patients [PDF]
Background/Aims: Transcatheter aortic valve implantation (TAVI) has emerged as a new therapeutic option for high-risk patients. However, dialysis patients were excluded from all previous studies.
Baglin A+25 more
core +1 more source
High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis [PDF]
Aims: High-sensitivity cardiac troponin I (cTnI) assays hold promise in detecting the transition from hypertrophy to heart failure in aortic stenosis.
A. L. Hunter+23 more
core +5 more sources
Possible predicative role of electrical risk score on transcatheter aortic valve replacement outcomes in older patients. preliminary data [PDF]
Background:Transcatheter aortic valve replacement (TAVR) is an effective procedure capable to change the natural history of the degenerative aortic valve stenosis.
DI IORIO, Claudia+9 more
core +1 more source
Aortic valve stenosis: Prognosis and therapy
There is a long latent period in the clinical course of aortic valve stenosis in adults. Symptoms usually occur in the case of critical stenosis, when aortic orifice area is under 0.7cm2 (0.4 cm2/m2). In this study 78 patients with critical aortic valve stenosis were investigated. The first manifestation of the disease was dyspnea (78.2%), angina (52.5%
Milorad Damnjanović+5 more
openaire +4 more sources
Prosthetic Aortic Valve Stenosis in End-Stage Renal Failure
Although renal failure is one of the known comorbidities associated with rapid progression of aortic stenosis, it is unclear whether hemodialysis alters the progression of prosthetic aortic valve stenosis.
Michael Mao+5 more
doaj +1 more source