Results 41 to 50 of about 118,216 (311)

Transcatheter versus surgical aortic valve replacement for stenotic bicuspid aortic valve: Systematic review and meta-analysisCentral MessagePerspective

JTCVS Open, 2023
Objectives: Bicuspid aortic valves have been excluded from randomized trials comparing transcatheter aortic valve replacement with surgical aortic valve replacement.
Yosuke Sakurai, MD, Yujiro Yokoyama, MD, Toshiki Kuno, MD, PhD, Hisato Takagi, MD, PhD, Amgad Mentias, MD, Vinod H. Thourani, MD, Azeem Latib, MD, Tsuyoshi Kaneko, MD   +7 more
doaj   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

One-stop transcatheter aortic valve replacement and fenestrated endovascular aortic aneurysm repair: A case report

Radiology Case Reports
The management of patients with severe aortic valve stenosis and an abdominal aortic aneurysm is a real therapeutic challenge. Minimally invasive treatment is more beneficial than open surgery for treating both aortic valve stenosis and abdominal aortic ...
Abderrahim Sanoussi, MD, Adel Aminian, MD, Jâd Abi-Khalil, MD   +2 more
doaj   +1 more source

Unicuspid Aortic Stenosis in a Patient with Turner Syndrome: A Case Report

Frontiers in Cardiovascular Medicine, 2014
Congenital aortic valve anomalies are the cause of premature aortic stenosis in pediatric and younger adult populations. Despite being very rare, unicuspid aortic valves account for approximately 5% of isolated aortic valve replacements.
Michael eEssandoh, Karina eCastellon-Larios, Alix eZuleta-Alarcon, Juan Guillermo Portillo, Juan A Crestanello   +4 more
doaj   +1 more source

Mortality Patterns and Phenotypic Clusters in Trisomy 13: A Population‐Based Study From Japan

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Trisomy 13, the third most common autosomal trisomy after trisomy 21 and trisomy 18, is associated with a significantly high infant mortality rate. However, large‐scale studies examining causes of death in trisomy 13 remain scarce. Therefore, we aimed to better understand the mortality patterns.
Narumi Kato, Naho Morisaki, Akinori Moriichi   +2 more
wiley   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

POSSIBILITIES OF INTERVENTIONAL CORRECTION OF CRITICAL AORTIC STENOSIS: CONTEMPORARY STATE OF PROBLEM AND PERSPECTIVES

Креативная хирургия и онкология, 2017
The paper studies the issues of aortic stenosis etiology and pathogenesis, clinical assessment of severity based on the distinct symptoms of decompensated aortic defect and echocardiographic measures, and modern methods of aortic stenosis correction ...
S. A. Amzaev, A. S. Sergeev, V. K. Sukhov, E. A. Shloydo, A. G. Obrezan   +4 more
doaj   +1 more source

Anterograde crossing of a bicuspid aortic valve through transseptal access to facilitate transcatheter aortic valve implantation

Heart Views, 2021
Transcatheter aortic valve implantation (TAVI) for bicuspid aortic valve stenosis can pose several technical challenges including difficult valve crossing.
Bilal Bawamia, Douglas Muir, Seth Vijayan, Paul Williams   +3 more
doaj   +1 more source

Midterm outcomes of aortic valve replacement using a rapid-deployment valve for aortic stenosis: TRANSFORM trial [PDF]

, 2023
S. Chris Malaisrie, Mubashir Mumtaz, Glenn R. Barnhart, Randolph W. Chitwood, William H. Ryan, Kevin Accola, Himanshu J. Patel, Y. Joseph Woo, Todd Dewey, Konstantinos Koulogiannis, Michael Dorsey, Eugene A. Grossi   +11 more
openalex   +1 more source

Left ventricular remodeling and hypertrophy in patients with aortic stenosis:insights from cardiovascular magnetic resonance [PDF]

, 2012
Background Cardiovascular magnetic resonance (CMR) is the gold standard non-invasive method for determining left ventricular (LV) mass and volume but has not been used previously to characterise the LV remodeling response in aortic stenosis. We sought to
Alpendurada, Francisco, Boon, Nicholas A, Cook, Stuart A, Dweck, Marc R, Gulati, Ankur, Jabbour, Andrew, Joshi, Sanjiv, Kilner, Philip J, Maceira, Alicia, Mohiaddin, Raad H, Murigu, Timothy, Newby, David E, Northridge, David B, Pennell, Dudley J, Pepper, John, Prasad, Sanjay K, Roussin, Isabelle   +16 more
core   +2 more sources