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Imaging of Genetic Thoracic Aortopathy

RadioGraphics, 2022
Aortopathy is a term most commonly used to describe a group of genetic diseases that predispose patients to an elevated risk of aortic events including aneurysm and acute aortic syndrome. Types of genetic aortopathy are classified as either heritable or congenital, with heritable thoracic aortic disease (HTAD) further subclassified into syndromic HTAD ...
Kacie L. Steinbrecher   +7 more
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The science of BAV aortopathy

Progress in Cardiovascular Diseases, 2020
The aortopathy associated with bicuspid aortic valve (BAV) is an epidemiologically relevant source of chronic and acute aortic disease (aneurysm and dissection). However, its pathogenesis is still the object of scientific uncertainties and debates. Indeed, the mechanisms determining the diseases of the ascending aorta in BAV patients are most likely ...
Lo Presti, Federica   +4 more
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Genetic Biomarkers in Aortopathy

Biomarkers in Medicine, 2013
The field of aortopathy, in common with other genomic disorders, is undergoing a revolution. This is largely driven by the implementation of newer forms of genetic sequencing (massively parallel or next-generation sequencing). Advantages conferred by this technology include reduced costs, reduced sequencing time and the ability to simultaneously test ...
Gillian, Rea, Fiona J, Stewart
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Inherited aortopathy: an overview

British Journal of Cardiac Nursing, 2023
This article is the fourth instalment of a wider series looking at cardiac genetic concepts. Inherited aortopathies are a group of syndromic and non-syndromic genetic conditions that affect the aorta. Aortopathies can lead to sudden cardiac death through aortic aneurysm rupture, especially in individuals whose aortopathy is undiagnosed.
Fortunate Mamombe   +7 more
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Aortopathy in Congenital Heart Disease

Cardiology Clinics, 2020
Aortic dilatation is common in patients with congenital heart disease and is seen in patients with bicuspid aortic valve and those with conotruncal congenital heart defects. It is important to identify patients with bicuspid aortic valve at high risk for aortic dissection.
Timothy B, Cotts   +3 more
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Aortopathy in pregnancy

Seminars in Perinatology, 2014
Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes.
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Idiopathic medial aortopathy and arteriopathy

The American Journal of Medicine, 1968
Abstract Five patients showing similar lesions in the aorta and its great branches are described. All showed patchy destruction of the elastic and muscle fibers of the media, with secondary fibrosis of the intima and sometimes of the adventitia. None had clinical or serologic evidence of syphilis.
Y, Marquis   +3 more
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Bicuspid aortic valve related aortopathy

General Thoracic and Cardiovascular Surgery, 2017
Bicuspid aortic valve related aortopathy is known to significantly increase the risk for catastrophic aortic events and, therefore, represents a considerable health burden. Albeit of ongoing research in this field including genetic, molecular, hemodynamic and morphologic aspects, bicuspid aortic valve related aortopathy still represents an imperfectly ...
Sina, Stock   +2 more
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Aortopathy: Effects of Lipid-Lowering Therapy

Cardiology in Review, 2023
Aortopathies can be congenital or acquired. Aortic atherosclerosis, abdominal aortic aneurysm, and degenerative aortic stenosis are some of the major manifestations of acquired aortopathy. Dyslipidemia, an imbalance of plasma lipid levels, is strongly associated with common aortopathies.
Matthew, Vollaro   +4 more
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Stenting in Aortopathies

2017
Transcatheter stent deployment within the aorta is generally used for two purposes: (1) relief of aortic obstruction as seen in aortic coarctation and (2) the use of covered stents to exclude an aneurysm or pseudoaneurysm of the aorta. For the purpose of relieving obstruction, balloon angioplasty alone is associated with reasonable short-term ...
Joanna Ghobrial, Jamil Aboulhosn
openaire   +1 more source

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