Results 71 to 80 of about 35,383 (222)

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

MedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun, Jiachen Qu, Sheng Peng, Yanan Hu, Amity Eliaz, Glenn M. Chertow, Isaac Eliaz, Zhiyong Peng   +7 more
wiley   +1 more source

Relationship between nutrition support and clinical outcomes in post–lung transplant patients in intensive care unit settings: A retrospective study

Nutrition in Clinical Practice, Volume 41, Issue 2, Page 516-529, April 2026.
Abstract Background Nutrition status significantly influences outcomes after solid organ transplantation, yet data on energy and protein intake in lung transplantation (LTx) patients in the intensive care unit (ICU) are scarce. The objective is to examine the medical nutrition therapy and clinical outcomes in mechanically ventilated post‐LTx adults ...
Malika Udagedara, Katherine J. P. Schwenger, Yasaman Ghorbani, Tulasi Patel, Maria Heusser, Deanna Zidar, Jordan Mak, Johane P. Allard   +7 more
wiley   +1 more source

Can the APACHE II score be used to assess the risk of mortality in the elderly with hip fractures?

Medicinski Glasnik
Aim Various predictive models have been developed to help identify patients with hip fractures with greater or lower probability of survival. The aim of this study was to establish the capacity of the APACHE II score to predict the survival of patients ...
Tarik Bujakovic, Samir Delibegovic
doaj   +1 more source

A Machine Learning‐Based Model for Individualized Prediction of Vancomycin Concentration‐Time Curves in ICU Patients

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
A machine learning–integrated pharmacokinetic model improves individualized prediction of vancomycin concentration–time profiles in ICU patients and outperforms traditional pharmacokinetic models, providing a practical decision‐support tool for precision dosing.
Jing‐Yi Wang, Jiang Hu, Yan Chen, Shan Li, Jin‐Min Peng, Run Dong, Xiao‐Yun Hu, Wei Jiang, Chun‐Yao Wang, Li Weng, Bin Du, the China Critical Care Clinical Trials Group (CCCCTG)   +11 more
wiley   +1 more source

Annual Reports to the ESA Council ESA 110th Annual Meeting July, 2025

The Bulletin of the Ecological Society of America, EarlyView.
wiley   +1 more source

Accelerating m‐Invariance for Continuous Big Data Publishing

IEEJ Transactions on Electrical and Electronic Engineering, Volume 21, Issue 4, Page 568-579, April 2026.
To prevent personal information leakage from the collection and publication of big data, anonymization techniques that protect privacy while preserving data utility are essential. In particular, m‐invariance provides privacy protection for dynamic datasets that are continuously published as records are updated.
Kentaro Morise, Hiroaki Nishi
wiley   +1 more source

Avaliação da gravidade de doentes ventilados numa unidade de cuidados intensivos respiratórios pelo sistema APACHE II.

Acta Médica Portuguesa, 1992
APACHE II system, is a simple and inexpensive method to evaluate severity of Intensive Care Patients. In a 2 years period (between 1988 and 1990), grading severity using APACHE II system, was performed on 498 consecutive mechanical Ventilated Patients in
G Brum, E Teixeira, C Barroso, F Monteiro, S Alves, V Magalhães, M Bastardo, A Couto, M F Freitas e Costa   +8 more
doaj   +1 more source

Mortality Predictions Including Pre‐Admission Functional Status in ICU Patients With Delirium—A Substudy of the AID‐ICU Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Purpose Pre‐admission functional status affects patients' ability to overcome the deteriorating effects of acute critical illness. We aimed to develop a clinical prediction model for 90‐day and 1‐year mortality based on pre‐admission data, including functional status, in adult delirious ICU patients. Methods We included participants randomized
Lone M. Poulsen, Andreas W. Rosen, Nina C. Andersen‐Ranberg, Camilla B. Mortensen, Anders Perner, Stine Estrup, Bodil S. Rasmussen, Ole Mathiesen   +7 more
wiley   +1 more source

Clinical effectiveness of procalcitonin‐ or C‐reactive protein‐guided antibiotic discontinuation protocols for adult patients who are critically ill with sepsis: a rapid systematic review and meta‐analysis

Anaesthesia, Volume 81, Issue 4, Page 556-569, April 2026.
Summary Introduction Antibiotics are a first‐line treatment for sepsis, with guidelines recommending a 7‐ to 10‐day course. Prolonged antibiotic use carries significant risks, prompting growing interest in using inflammatory biomarkers, such as procalcitonin or C‐reactive protein, to guide clinical decision‐making on the duration of antibiotic therapy ...
Sonya Rafiq, Chunhu Shi, Shraboni Ghosal, Paul Dark, Tim Felton, Evangelos Kontopantelis, Jo Dumville   +6 more
wiley   +1 more source

NeuralFlux: Estimation of Reaction Fluxes at a Genome‐Scale Level From Time‐Resolved Isotope Labelling Patterns Using Deep Learning

Plant Biotechnology Journal, EarlyView.
Sebastian Huß, Zoran Nikoloski
wiley   +1 more source