Results 191 to 200 of about 60,941 (262)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Twenty-six-year trends in U.S. mortality among older adults with coexisting chronic kidney disease and atrial fibrillation/flutter. [PDF]

Ann Med Surg (Lond)
Kumar S, Zulfiqar R, Khan S, Malik W, Rehman A, Arshia F, Junaid Imran M, Nouman A, Naz H, Kumar L, Muhammad Asif H, Khan T, Raja A, Chaulagain A.   +13 more
europepmc   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Mortality Trends in the United States due to Concurrent Heart Failure, Atrial Fibrillation/Flutter and Sepsis. [PDF]

Cardiol Cardiovasc Med
Shanmuganathan G, Lee NJ, Agrawal DK.
europepmc   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Demographic trends in mortality related to Alzheimer's disease and pneumonia: a two-decade (1999-2022) analysis from the CDC WONDER database. [PDF]

Ann Med Surg (Lond)
Faisal AR, Singh P, Hassan M, Laiba F, Zaman A, Hafeez AS, Abdullah, Faizan M, Ashraf MU, Zahoor M, Alam MM, Maity R, Dhali A.   +12 more
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Hypertensive kidney disease with concurrent diabetes mellitus: national mortality trends from CDC WONDER 1999-2024. [PDF]

Ann Med Surg (Lond)
Pervaiz A, Jamali JA, Mohsin Zahoor M, Saqib Usman M, Devi K, Kumar M, Simran F, Ali Z, Muhammad N, Raja R, Khalil M, Anchal F, Tesfaye M.   +12 more
europepmc   +1 more source

Inline Oxygenation in Drip‐Irrigated Citrus: How Much Agrochemical Reduction Is Needed to Achieve Net Environmental Benefits?

Irrigation and Drainage, EarlyView.
ABSTRACT The agronomic benefits of oxygen‐enriched irrigation, such as improved root development, enhanced nutrient uptake, and reduced fertiliser and pesticide requirements, are well documented. However, incorporating oxygenation devices into fertigation systems increases energy demand and material use, thereby incurring additional environmental ...
Alberto Imbernón‐Mulero, Saker Ben Abdallah, Mohamed Zied Dhraief, Jose F. Maestre‐Valero, Belén Gallego‐Elvira   +4 more
wiley   +1 more source

Extra-abdominal Desmoid Tumor in a 23-Year-Old Male: A Case Report. [PDF]

Cureus
Boyett R, Sisson J, Overbeek TL, Wilbanks B, Read CR.   +4 more
europepmc   +1 more source