Results 21 to 30 of about 60,941 (262)

Novel mutations and phenotypic associations identified through APC, MUTYH, NTHL1, POLD1, POLE gene analysis in Indian Familial Adenomatous Polyposis cohort

open access: yesScientific Reports, 2017
Colo-Rectal Cancer is a common cancer worldwide with 5–10% cases being hereditary. Familial Adenomatous Polyposis (FAP) syndrome is due to germline mutations in the APC or rarely MUTYH gene.
Nikhat Khan   +4 more
doaj   +1 more source

The effects of positive thinking education for adolescent girls on their conflicts with their mothers: A randomized controlled trial

open access: yesNursing and Midwifery Studies, 2022
Background: Adolescent–parent conflict (APC) has damaging effects on both adolescents and parents and hence effective strategies for its management are necessary.
Fatemeh Nematian   +3 more
doaj   +1 more source

A Field Study of Internet of Things-Based Solutions for Automatic Passenger Counting

open access: yesIEEE Open Journal of Intelligent Transportation Systems, 2021
The planning of public transport operations is an essential component of urban transport management systems that aims to provide the most efficient, safe and effective way to support movement of people.
Chris Mccarthy   +11 more
doaj   +1 more source

Atypical APC-1 pelvic fracture presenting with pelvic instability: successful management with pubic symphysis fusion

open access: yesBMJ Case Reports, 2022
By definition, anteroposterior (AP) compression type 1 (APC-1) injury is a type of pelvic ring injury, which is widely acknowledged as ‘stable’. Unstable forms of this injury are very rare and present a challenge for diagnosis and clinical management. Detailed herein is a man in his early 30s, referred to our institution with a 2-year history of pubic ...
Sophia M Wakefield   +3 more
openaire   +2 more sources

Auditing Protein Therapeutics Management by Professional APCs: Toward Prevention of Immune Responses against Therapeutic Proteins [PDF]

open access: yesThe Journal of Immunology, 2008
Abstract Alloimmunization is a crippling concern in the management of patients undergoing administration of protein therapeutics as evidenced in replacement therapy and other treatment procedures. Several issues in the genesis and modulation of such deleterious immune responses have been studied.
Suryasarathi, Dasgupta   +5 more
openaire   +2 more sources

Interactions of Publication Volume, Journal Impact, and Article Processing Charges: Comparative Study of China and Global Practices in Nature Portfolio

open access: yesPublications
In the commercial realm, the annual publication volume (PUB) significantly influences the business models of article processing charge (APC)-based open access (OA) journals, though it may negatively impact journal reputation.
Xinyi Chen
doaj   +1 more source

Genotype-guided conservative management of mesenteric desmoid tumors: A case report of intermediate-region APC mutations. [PDF]

open access: yesMedicine (Baltimore)
Rationale: Desmoid tumors (DTs) exhibit highly variable behavior, making management challenging. Specific adenomatous polyposis coli (APC) gene mutation sites are recognized as key prognostic markers, potentially enabling genotype-guided strategies to avoid overtreatment.
Huang N, Shi G, Luo XL.
europepmc   +3 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Safety and efficacy of endoscopic band ligation versus argon plasma coagulation in management of gastric antral vascular ectasia: randomized clinical trial

open access: yesThe Egyptian Journal of Internal Medicine
Background Endoscopic management of gastric antral vascular ectasia (GAVE) is challenging. Most of the published studies investigated the role of argon plasma coagulation (APC).
Esraa Y. M. Swifee   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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