Results 41 to 50 of about 115,603 (289)

Research progress of amorphous photonic crystals prepared by self-assembly

Next Materials
In nature, organisms or non-organisms have produced brilliant structural colors in the process of evolution. The structural color remains stable and will not produce chemical pollution.
Yaorui Hao, Yuyang Han, Xiao Huang, Fen Wang, Hongjie Luo   +4 more
doaj   +1 more source

Intestinal macromolecular transport supporting adaptive immunity [PDF]

, 2019
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A new approach to APCs

EMBO Reports
The article processing charges associated with open-access publishing are unaffordable for some scientists. One solution is to break the APC down into its component parts, enabling scientists to spread the costs over multiple providers and several years.
Fiona M Watt
doaj   +1 more source

Measuring patient acuity and nursing care needs in South Korea: application of a new patient classification system

BMC Nursing, 2022
Background An accurate and reliable patient classification system (PCS) can help inform decisions regarding adequate assignments for nurse staffing. This study aimed to evaluate the criterion validity of the Asan Patient Classification System (APCS), a ...
Jeounghee Kim, TaeRim Kang, Hyun-Ju Seo, So-Young Seo, Myoungsook Kim, Youngsun Jung, Jinhyun Kim, Jung- Bok Lee   +7 more
doaj   +1 more source

The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]

, 2015
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita, CHIANTORE, Maria Vincenza, Fiorucci, Gianna, IULIANO, MARCO, MANGINO, GIORGIO, ROMEO, Giovanna, Tommasino, Massimo   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Single-cell analysis reveals a subpopulation of adipose progenitor cells that impairs glucose homeostasis

Nature Communications
Adipose progenitor cells (APCs) are heterogeneous stromal cells and help to maintain metabolic homeostasis. However, the influence of obesity on human APC heterogeneity and the role of APC subpopulations on regulating glucose homeostasis remain unknown ...
Hongdong Wang, Yanhua Du, Shanshan Huang, Xitai Sun, Youqiong Ye, Haixiang Sun, Xuehui Chu, Xiaodong Shan, Yue Yuan, Lei Shen, Yan Bi   +10 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Peperomin E and its orally bioavailable analog induce oxidative stress-mediated apoptosis of acute myeloid leukemia progenitor cells by targeting thioredoxin reductase

Redox Biology, 2019
The early immature CD34+ acute myeloid leukemia (AML) cell subpopulation-acute myeloid leukemia progenitor cells (APCs), is often resistant to conventional chemotherapy, making them largely responsible for the relapse of AML.
Xinzhi Wang, Ming Gao, Jiyun Zhang, Ying Ma, Wenshu Qu, Jingyu Liang, Hao Wu, Hongmei Wen   +7 more
doaj   +1 more source