Results 191 to 200 of about 664,049 (296)

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Influencing Factors and Optimization of Coal Fines Transportability in Mine Borehole Screen Pipes. [PDF]

ACS Omega
Zhang X, Tian K, Gao J, Wang Y, Liu Q, Hui X, Li Q.   +6 more
europepmc   +1 more source

Polymer‐in‐Cage Strategy for Pore Tuning of High‐Aspect Ratio ZIF Nanoplate: Toward Sub‐Micrometer‐Thick Large Area CO2 Separation Membranes

Advanced Science, EarlyView.
A “polymer‐in‐cage” strategy transforms a zinc‐acrylate copolymer into an active pore‐modulating agent for ZIF‐8 nanoplates. The polymer actively tunes the MOF's pore structure by anchoring within its windows, while the nanoplates create tortuous pathways.
Minsu Kim, Hyo Jun Min, Min Kyu Choi, Ki Chul Kim, Bomi Kim, Miso Kang, Nahyeon Lee, Kiwon Eum, Jong Hak Kim, Dae Woo Kim   +9 more
wiley   +1 more source

Ethylene participates in strigolactone-triggered stomatal closure via Gα protein-activited hydrogen peroxide and hydrogen sulfide synthesis in <i>Arabidopsis</i>. [PDF]

Front Plant Sci
Ma Y, Zhao Z, Song Y, Chai S, Zhao H, Liang S.   +5 more
europepmc   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

Advanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang, Zi‐Bin Lin, Zhuo Chen, Zhao‐Hui Liu, Jin‐Lian He, Jun‐Jie Song, Long‐Sheng Zeng, Liang Zhou, Ming‐Yue Ding, Yu‐Gui Peng, Ming Yuchi, Xue‐Feng Zhu   +11 more
wiley   +1 more source

Semi-Automatic Artificial Lips Device for Brass Instruments with Real-Time Pitch Feedback Control. [PDF]

Sensors (Basel)
Sonoda H, Kuriyama H, Tomiyoshi K, Koutaki G.   +3 more
europepmc   +1 more source

Study of Free‐Space Optical Quantum Network: Review and Prospectives

Advanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

Development and Phantom Validation of a Small-Form-Factor SWIR Emitter Probe for Hydration-Sensitive Spatial-Ratio Measurements in Gelatin-Intralipid Phantoms. [PDF]

Sensors (Basel)
Farouq G, Vyas D, Tofghi Zavareh A.
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source