Results 11 to 20 of about 21,800 (268)

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter   +14 more
wiley   +1 more source

Effect on haemostasis of different replacement fluids during therapeutic plasma exchange—A comparative multicentre observational study

open access: yesJournal of Clinical Apheresis, Volume 37, Issue 6, Page 534-543, December 2022., 2022
Abstract Introduction Therapeutic plasma exchange (TPE) is used for several chronic conditions with little evidence on the efficacy and safety of different choice of replacement fluid. Measurement of haemostasis, particularly in vitro thrombin generation, could play a role in determining the immediate efficacy of different fluid replacement.
Ruchika Kohli   +6 more
wiley   +1 more source

The safety and performance of the Spectra Optia apheresis system platelet depletion protocol in patients with elevated platelet counts

open access: yesJournal of Clinical Apheresis, Volume 37, Issue 6, Page 544-552, December 2022., 2022
Abstract Background Thrombocytosis is a presenting and progressive clinical feature found in multiple disease states. It is characterized by high platelet (PLT) counts (>450 × 109/L) and can lead to thrombohemorrhagic events. Thrombocytapheresis or platelet depletion (PLTD) can be performed in acutely symptomatic patients suffering from thrombocytosis ...
Pamela Lopert   +13 more
wiley   +1 more source

Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis

open access: yesScientific Reports, 2021
For peritonitis, a serious complication of peritoneal dialysis (PD), we investigated the relation between duration from the sign (PD effluent abnormalities) to treatment with appropriate antibiotics (ST time) and catheter removal.
Rikako Oki   +9 more
doaj   +1 more source

Tocilizumab and Active Antibody-Mediated Rejection in Kidney Transplantation: A Literature Review

open access: yesFrontiers in Immunology, 2022
IntroductionChronic kidney disease (CKD) is a major public-health problem that increases the risk of end-stage kidney disease (ESKD), cardiovascular diseases, and other complications.
Lara Cabezas   +10 more
doaj   +1 more source

Therapeutic plasma exchange in adolescent and adult patients with autoimmune neuropsychiatric disorders associated with streptococcal infections

open access: yesJournal of Clinical Apheresis, Volume 37, Issue 6, Page 597-599, December 2022., 2022
Abstract Pediatric autoimmune neuropsychiatric disorders associated with streptococcal (PANDAS) infections and pediatric acute‐onset neuropsychiatric syndrome (PANS) are typically diagnosed in childhood. Therapeutic plasma exchange (TPE) has been recommended to remove relevant antibodies and treat symptomatic presentations in children and adolescents ...
Kristina Prus   +2 more
wiley   +1 more source

Platelet‐rich plasma versus corticosteroid injections in the management of patients with rotator cuff disease: A systematic review and meta‐analysis

open access: yesJournal of Orthopaedic Research, Volume 41, Issue 1, Page 7-20, January 2023., 2023
Abstract Platelet‐rich plasma (PRP) is an alternative to corticosteroid (CS) injections in managing rotator cuff disease. This meta‐analysis investigated differences between PRP and CS for function and pain scores in significance and minimal clinical important difference (MCID).
Maamoun Adra   +8 more
wiley   +1 more source

Primary antiphospholipid syndrome associated with anti-phospholipase A2 receptor antibody-positive membranous nephropathy

open access: yesBMC Nephrology, 2020
Background The kidney is a major target in primary antiphospholipid syndrome. Several types of nephropathy have been reported, the most frequent being acute or chronic specific vascular nephropathies and membranous nephropathy.
Maxime Teisseyre   +6 more
doaj   +1 more source

Epidemiological survey of patients with pustular psoriasis in the Japanese Society for Psoriasis Research from 2017 to 2020

open access: yesThe Journal of Dermatology, Volume 50, Issue 1, Page 3-11, January 2023., 2023
Abstract The Japanese Society for Psoriasis Research (JSPR) has been conducting annual epidemiological surveys of patients with pustular psoriasis in Japan since 2017. This study aimed to conduct a recent epidemiological analysis of patients with pustular psoriasis who were enrolled in the JSPR from 2017 to 2020.
Koji Kamiya, Mamitaro Ohtsuki
wiley   +1 more source

Research progress of iron deficiency in apheresis donors

open access: yesZhongguo shuxue zazhi, 2022
Objective The loss of iron stores is well documented in whole blood donors, and a large number of studies have confirmed that blood donors are at risk of iron deficiency.
Guanglin XIAO   +3 more
doaj   +1 more source

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