Results 51 to 60 of about 21,800 (268)

Automated analysis of flow cytometry data with minimal training files: Research evaluation of an elastic image registration algorithm for TBNK, stem cell enumeration, and lymphoid screening tube assays

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Automated analysis of flow cytometry data can improve objectivity and reduce analysis time but has generally required work by software and algorithm experts. Here, we investigated the performance of BD ElastiGate™ Software (hereafter ElastiGate), which allows users to automate gating by selecting gated training files, then uses elastic image ...
Allison Irvine, Suhail Tahir, Vishnu Tripathi, Farzad Oreizy, Moen Sen, Anthony Giuliano, Anna Lin, Angela Chen, Chih‐Hung Lai, Imelda Omana‐Zapata, Yang Zeng, Paresh Jain, Scott J. Bornheimer   +12 more
wiley   +1 more source

Case report: C-reactive protein apheresis in cardiogenic shock: case series from the C-reactive protein apheresis in acute myocardial infarction-registry

Frontiers in Drug Discovery, 2023
C-reactive protein (CRP) apheresis may preserve myocardial tissue after acute myocardial infarction with delayed revascularization. Ten consecutive patients with cardiogenic shock were graded using the Society of Cardiovascular Angiography and ...
J. Torzewski, S. Mattecka, W. Ries, C. D. Garlichs, F. Heigl, J. Fiedler, A. Sheriff, A. Sheriff   +7 more
doaj   +1 more source

Catheter Diversion Procedure With Exit-Site Renewal Promotes Peritoneal Dialysis Catheter Survival

Kidney International Reports, 2021
Introduction: Catheter-related infections such as exit site infection (ESI) and tunnel infection (TI) are major causes of peritoneal dialysis (PD) discontinuation.
Rikako Oki, Yoshifumi Hamasaki, Yohei Komaru, Yoshihisa Miyamoto, Ryo Matsuura, Daisuke Yamada, Masao Iwagami, Kent Doi, Haruki Kume, Masaomi Nangaku   +9 more
doaj  

Preoperative Low-Density Lipoprotein Apheresis for Preventing Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation

Journal of Transplantation, 2018
Background. Focal segmental glomerulosclerosis (FSGS) often develops rapidly and frequently progresses to renal failure, while the recurrence rate after kidney transplantation is 20–50%.
Akihito Sannomiya, Toru Murakami, Ichiro Koyama, Kosaku Nitta, Ichiro Nakajima, Shohei Fuchinoue   +5 more
doaj   +1 more source

Safety and feasibility of apheresis to harvest and concentrate parasites from subjects with induced blood stage Plasmodium vivax infection

Malaria Journal, 2021
Background In the absence of a method to culture Plasmodium vivax, the only way to source parasites is ex vivo. This hampers many aspects of P. vivax research. This study aimed to assess the safety of apheresis, a method for selective removal of specific
Anand Odedra, Kari Mudie, Glen Kennedy, Rebecca E. Watts, Emilie Rossignol, Hayley Mitchell, Jeremy Gower, Maria Rebelo, Zuleima Pava, Rebecca Pawliw, Stephen Woolley, David G. Lalloo, Greg Robinson, Sean Lynch, Katharine A. Collins, Fiona Amante, James McCarthy   +16 more
doaj   +1 more source

Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH). A population pharmacokinetic (PK)/pharmacodynamic (PD) model was previously developed to characterize ...
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
wiley   +1 more source

Comparison of Model‐Predicted and Observed Evinacumab Pharmacokinetics and Efficacy in Children Aged < 5 Years With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C) in patients with homozygous familial hypercholesterolemia (HoFH). Herein, we report pharmacokinetic and efficacy analyses of evinacumab in < 5‐year‐old patients with HoFH.
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Katy C. Norman, Richard T. George, Xue‐Qiao Zhao, Robert Pordy, Daniel Garcia, Wendy S. Putnam, Geetha Raghuveer, Brian W. McCrindle, Elena Fornari, Ivo Baric, Shubha Srinivasan, Melissa Diamond, Eliot A. Brinton, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +18 more
wiley   +1 more source

Urinary Neopterin and Microalbuminuria in Patients Treated by Low-density Lipoprotein Apheresis

Pteridines, 2005
Low-density lipoprotein (LDL)-apheresis is a method of extracorporeal elimination of LDL-cholesterol in patients with severe primary lipoprotein disorders.
Cermanová Melanie, Melichar Bohuslav, Solichová Dagmar, Bláha Milan, Bláha Vladimir, Blazek Martin, Mašín Vladimir, Cerman Jaroslav, Zadák Zdenek   +8 more
doaj   +1 more source

Impact of frequent apheresis blood donation on bone density: A prospective, longitudinal, randomized, controlled trial

Bone Reports, 2019
Background: Blood for transfusion is lifesaving and essential to many elements of modern medical practice. The global blood supply relies on volunteer blood donors.
Walter Bialkowski, Robert D. Blank, Cheng Zheng, Jerome L. Gottschall, Paula E. Papanek   +4 more
doaj  

Lipoprotein turnover and possible remnant accumulation in preeclampsia: insights from the Freiburg Preeclampsia H.E.L.P.-apheresis study

Lipids in Health and Disease, 2018
Background Preeclampsia is a life-threatening disease in pregnancy, and its complex pathomechanisms are poorly understood. In preeclampsia, lipid metabolism is substantially altered.
Christine Contini, Martin Jansen, Brigitte König, Filiz Markfeld-Erol, Mirjam Kunze, Stefan Zschiedrich, Ulrich Massing, Irmgard Merfort, Heinrich Prömpeler, Ulrich Pecks, Karl Winkler, Gerhard Pütz   +11 more
doaj   +1 more source