Results 91 to 100 of about 3,368 (278)

Mondia whitei (Periplocaceae) prevents and Guibourtia tessmannii (Caesalpiniaceae) facilitates fictive ejaculation in spinal male rats

open access: yesBMC Complementary and Alternative Medicine, 2013
Background Mondia whitei and Guibourtia tessmannii are used in Cameroon traditional medicine as aphrodisiacs. The present study was undertaken to evaluate the pro-ejaculatory effects of the aqueous and organic solvent extracts of these plants in spinal ...
Watcho Pierre   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Assorted Avocational Adventures [PDF]

open access: yes, 1981
Adults, an array, are abjectly abashed at alliteration\u27s ancient appeal as attractive (and auspicious?) abracadabra. Another array abhors and abominates alliteration as airy artifice.
Austrian, Amelia
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Aphrodisiac Activity of Clove Leaves (Syzygium aromaticum L.) Ethanol Extract and Fractions in Wistar rats

open access: yesSciences of Phytochemistry
Erectile dysfunction (ED) and premature ejaculation are prevalent male sexual dysfunctions affecting various age groups. This study explores the potential aphrodisiac effects of Clove leaves (Syzygium aromaticum L.), a plant rich in secondary metabolites,
Rezky Yanuarty   +2 more
doaj   +1 more source

Yogis, Ayurveda, and Kayakalpa: The Rejuvenation of Pandit Malaviya [PDF]

open access: yes, 2017
How should we read claims about health and well-being which defy common sense? Are claims of extreme longevity to be viewed as fraudulent, or as pushing the boundaries of possibility for the human body?
Newcombe, Suzanne
core   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Rekindling desire: Unveiling the Aphrodisiac potential of Apiaceae Elixirs

open access: yesPhytomedicine Plus
Background: In the realms of herbal pharmacology, the Apiaceae family has long held the torch, with parsley, coriander, and celery at the forefront. They have been extensively utilized in traditional therapies, including their use as aphrodisiacs.
Ghizlane Nouioura   +2 more
doaj   +1 more source

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