Results 181 to 190 of about 857,518 (248)

Engineering Organoid Platforms for Pathogenesis Research. [PDF]

Research (Wash D C)
Han X, Zhang J, Bai J, Tian W, Zhou J, Ding L, Gao X.   +6 more
europepmc   +1 more source

Simplified SPAL technique to provide adequate peri‐implant phenotype: A pilot study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Correction of peri‐implant bone dehiscence (PIBD) and optimization of the peri‐implant soft‐tissue phenotype are critical for long‐term peri‐implant tissues stability. A simplified, one‐stage, transmucosal variant of the subperiosteal peri‐implant augmented layer (sSPAL) technique was appraised and evaluated.
Leonardo Trombelli, Chiara Franzini, Mattia Severi   +2 more
wiley   +1 more source

An innovative organoid model to screen for bacteria and their metabolites that protect against inflammation-induced colonic barrier disruption. [PDF]

mSphere
Cady N, Meyer SR, Kim K, Lo BC, So N, Chen GY, Rosshart SP, Shah YM, Núñez G, Sexton JZ, Schmidt TM.   +10 more
europepmc   +1 more source

Sequential regenerative therapy using biologic‐based regeneration and connective tissue graft wall technique for a severe infrabony defect: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Regenerative therapy based on the principles of guided tissue regeneration (GTR) is an effective approach for the treatment of periodontal infrabony defects. However, complete resolution for deep and complex defects is not always predictable.
Wenwen Liu, Yilong Chen, Muhammad Saleh, Hom‐Lay Wang   +3 more
wiley   +1 more source

LIM domain-containing proteins Zyxin and LPP localize to apical epithelial cell-cell junctions at regions of stable F-actin. [PDF]

MicroPubl Biol
Tjoelker KK, Bashirzadeh Y, Beel LM, Liu AP, Miller AL.   +4 more
europepmc   +1 more source

Connective tissue graft wall technique for mandibular Class II furcation defects: Two case reports

Clinical Advances in Periodontics, EarlyView.
Abstract Background Furcation involvement (FI) represents one of the most challenging conditions in periodontal therapy due to limited accessibility and the progressive interradicular attachment loss that compromises long‐term tooth stability. Deep periodontal pockets in molars and premolars often present as combined defects, including horizontal FI ...
Ilham Mounssif, Martina Stefanini, Valentina Bentivogli, Diego Bianchelli, Chia Ming Kuo, Matteo Sangiorgi, Claudio Mazzotti, Giovanni Zucchelli   +7 more
wiley   +1 more source

SARS-CoV-2 disrupts the integrity of a human blood-brain barrier model in the absence of infection. [PDF]

J Neurovirol
Jmii H, Haverty R, Rochfort KD, Fletcher NF.   +3 more
europepmc   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Advances in New Approach Methodologies at FDA's Division of Applied Regulatory Science

Clinical Pharmacology &Therapeutics, EarlyView.
New Approach Methodologies (NAMs) represent a paradigm shift in drug development and regulatory science, offering human‐relevant alternatives to traditional preclinical models. This mini‐review highlights recent advances in NAM development, validation, and regulatory application from FDA's Division of Applied Regulatory Science (DARS).
Ksenia Blinova, Kimberly Chiu, Anik Chaturbedi, Jahan Cooper, Tromondae K. Feaster, Paula L. Hyland, Lidiya Stavitskaya, Wendy W. Wu, Jeffry Florian, Rodney Rouse   +9 more
wiley   +1 more source

A Practical Gut-On-Chip Workflow for Imaging-Based Assessment of Epithelial Barrier Dynamics During E. coli Co-Culture. [PDF]

Biotechnol Bioeng
Chiang SW, Yang CY, Chen GY.
europepmc   +1 more source