Results 11 to 20 of about 3,530,570 (320)

Effective Apical Infection of Differentiated Human Bronchial Epithelial Cells and Induction of Proinflammatory Chemokines by the Highly Pneumotropic Human Adenovirus Type 14p1. [PDF]

open access: yesPLoS ONE, 2015
Only a few pneumotropic types of the human adenoviruses (e.g. type B14p1) cause severe lower respiratory tract infections like pneumonia and acute respiratory distress syndrome (ARDS) even in immunocompetent patients.
Elena Lam   +6 more
doaj   +2 more sources

Recent Advances in Apical Periodontitis Treatment: A Narrative Review

open access: yesBioengineering, 2023
Apical periodontitis is an inflammatory response caused by pulp infection. It induces bone resorption in the apical and periapical regions of the tooth. The most conservative approach to treat this condition is nonsurgical endodontic treatment.
Zulema Arias   +7 more
doaj   +2 more sources

New insight into Epstein-Barr virus infection using models of stratified epithelium.

open access: yesPLoS Pathogens, 2023
Epstein-Barr virus (EBV) is a ubiquitous human pathogen that is transmitted in saliva. EBV transits through the oral epithelium to infect B cells, where it establishes a life-long latent infection. Reinfection of the epithelium is believed to be mediated
Ian R Hayman   +6 more
doaj   +2 more sources

Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs

open access: yesScientific Reports, 2022
Airway organoids are polarized 3D epithelial structures that recapitulate the organization and many of the key functions of the in vivo tissue. They present an attractive model that can overcome some of the limitations of traditional 2D and Air–Liquid ...
Georgios Stroulios   +12 more
doaj   +2 more sources

Association between Endodontic Infection, Its Treatment and Systemic Health: A Narrative Review

open access: yesMedicina, 2022
The ‘Focal Infection Era in Dentistry’ in the late 19th and early 20th century resulted in widespread implementation of tooth extraction and limited the progress of endodontics.
Sadia Ambreen Niazi, Abdulaziz Bakhsh
doaj   +2 more sources

Primary differentiated respiratory epithelial cells respond to apical measles virus infection by shedding multinucleated giant cells

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
Significance Measles virus (MeV) is highly infectious by the respiratory route, but respiratory epithelial cells are thought to be resistant to infection through the exposed apical surface and to require infection through the basolateral surface. We show
Wen-Hsuan W. Lin   +4 more
semanticscholar   +1 more source

Adenovirus entry from the apical surface of polarized epithelia is facilitated by the host innate immune response. [PDF]

open access: yesPLoS Pathogens, 2015
Prevention of viral-induced respiratory disease begins with an understanding of the factors that increase or decrease susceptibility to viral infection.
Poornima L N Kotha   +7 more
doaj   +1 more source

The Coxsackievirus and Adenovirus Receptor Has a Short Half-Life in Epithelial Cells

open access: yesPathogens, 2022
The coxsackievirus and adenovirus receptor (CAR) is an essential cellular protein that is involved in cell adhesion, cell signaling, and viral infection.
Poornima Kotha Lakshmi Narayan   +8 more
doaj   +1 more source

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