Preferential apical infection of Caco-2 intestinal cell monolayers by SARS-CoV-2 is associated with damage to cellular barrier integrity: Implications for the pathophysiology of COVID-19. [PDF]
PLoS ONESARS-CoV-2 can infect different organs, including the intestine. In an in vitro model of Caco-2 intestinal cell line, we previously found that SARS-CoV-2 modulates the ACE2 receptor expression and affects the expression of molecules involved in ...
Clémence Garrec +6 more
doaj +3 more sources
RSV can infect the human nasal epithelium via the basolateral route and shows distinct subgroup infectivity and basal cell tropism [PDF]
Journal of VirologyRespiratory syncytial virus (RSV) causes millions of lower respiratory tract infections (LRTIs) in young children, older adults, and immunocompromised populations every year.
Ashley Murray +7 more
doaj +2 more sources
Molecular Pain, 2020 Infection-induced chronic pain is an under-studied pain condition. One example is apical periodontitis, which evokes considerable mechanical allodynia that persists after treatment in 7% to 12% of patients.
Nikita B Ruparel, Obadah Austah
exaly +2 more sources
Apical-Out Human Airway Organoids Modeling SARS-CoV-2 Infection
Viruses, 2023 The respiratory epithelium, particularly the airway epithelium, is the primary infection site for respiratory pathogens. The apical surface of epithelial cells is constantly exposed to external stimuli including invading pathogens. Efforts have been made
Man Chun Chiu +8 more
doaj +2 more sources
Multifactorial Analysis Identifies Conditions for Robust HCoV-OC43 Replication in Primary Human Bronchial Epithelial Cells Cultured at Air–Liquid Interface [PDF]
CellsAir–liquid interface (ALI) cultures recapitulate key features of the airway epithelium by driving basal cell differentiation into ciliated, club, and goblet cells and by generating a functional mucus barrier, thereby representing a highly relevant model ...
Natalie Fischhaber +3 more
doaj +2 more sources
Apical hypertrophic cardiomyopathy associated with HCV infection
Терапевтический архив, 2011 A case is reported of a female patient with apical hypertrophic cardiomyopathy with negative chest T waves associated with HCV infection.
Viktor Viktorovich Fomin +11 more
doaj +3 more sources
Frontiers in Veterinary Science, 2022 BackgroundOral health in alpacas is often neglected until severe dental disease becomes evident under the form of a pronounced mandibular swelling with or without fistulation.
Kirsten Proost +2 more
doaj +1 more source
Emerging Microbes and Infections, 2023 Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan +8 more
doaj +1 more source
Adenovirus entry from the apical surface of polarized epithelia is facilitated by the host innate immune response. [PDF]
PLoS Pathogens, 2015 Prevention of viral-induced respiratory disease begins with an understanding of the factors that increase or decrease susceptibility to viral infection.
Poornima L N Kotha +7 more
doaj +1 more source
Malignant arrhythmia in apical ballooning syndrome: risk factors and outcomes. [PDF]
, 2008 Objectives: We sought to determine the frequency and outcomes with symptomatic arrhythmia in patients with apical ballooning syndrome (ABS). Methods: A retrospective review of the Mayo Clinic Angiography database was conducted to identify patients who
Prasad, A +6 more
core +3 more sources