Results 81 to 90 of about 4,923,857 (294)

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

open access: yesAdvanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma   +18 more
wiley   +1 more source

Microapical surgery of a periapical cyst caused by apical ramification: a case report and review of the literature

open access: yesJournal of Medical Case Reports
Background The destruction of tooth apical bone mainly comes from odontogenic apical cysts caused by pulp necrosis, chronic inflammation, or trauma. Some affected teeth can be cured by modern root canal treatment or non-surgical retreatment, but some ...
Liyun Bai   +9 more
doaj   +1 more source

Single incision anterior apical mesh and sacrospinous ligament fixation in pelvic prolapse surgery at 36 months follow-up

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2017
Objective: To compare the clinical efficacy, recurrence, complications and quality of life changes 3 years after Elevate-A/single incision mesh surgery anterior apical (SIM A) and sacrospinous ligament fixation (SSF) in the management of pelvic organ ...
Tsia-Shu Lo   +5 more
doaj   +1 more source

Scarring of gingiva and alveolar mucosa following apical surgery: a visual assessment after one year

open access: yes, 2008
Aim: (1) To visually assess scarring of the gingiva and alveolar mucosa 1 year following apical surgery in the aesthetic zone; and (2) to evaluate whether scarring correlated with patient-related or surgical parameters. Material and methods: The material
Salvi, G. E.   +11 more
core   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

open access: yesAdvanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu   +13 more
wiley   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

open access: yesAdvanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth   +20 more
wiley   +1 more source

Histologic evaluation of the use of membrane, bone graft, and MTA in apical surgery

open access: yes, 2010
The aim of this study was to evaluate the periapical healing after the use of membrane, bone graft, and mineral trioxide aggregate (MTA) in apical surgery of dogs' teeth.
Moretto, Marcelo Juliano [UNESP]   +25 more
core   +1 more source

Prognostic factors in apical surgery with root-end filling: a meta-analysis [PDF]

open access: yes, 2010
INTRODUCTION: Apical surgery has seen continuous development with regard to equipment and surgical technique. However, there is still a shortage of evidence-based information regarding healing determinants.
Jensen, Storgård   +10 more
core   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

open access: yesAdvanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi   +16 more
wiley   +1 more source

Successful Surgical Outcome for an Endodontic Failure using Biodentine™ as Retrograde Restoration in Conjunction with Platelet Rich Fibrin (PRF) for Progressive Healing [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Ajinkya Mansing Pawar   +3 more
doaj   +1 more source

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