Results 181 to 190 of about 111,354 (312)

The natural mechanism of suppression of Nosema apis Zander in enzootically infected colonies of the honey bee, Apis mellifera Linnaeus

, 1959
Honey bees, artificially infected with Nosema apis Zander and introduced into an enzootically infected colony in summer when infection was naturally diminishing, were all infected and developed similar numbers of spores to those in naturally infected ...
Bailey, L.
core  

Evaluation of Human-Approved Active Pharmaceutical Ingredients Against Lactate Dehydrogenase from Theileria annulata. [PDF]

Acta Parasitol
Akar S, Orlenco M, Ugurel E, Danış Ö, Turgut-Balik D.   +4 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Mechanistic Comparison of Semi-Solid Extrusion 3D-Printed Printlets and Hot-Moulded Tablets: Linking Polymer-API Interactions, Microstructure, and Dissolution of Plant-Based Formulations. [PDF]

Pharmaceutics
Nemickaite E, Todke P, Cicenas V, Jasiūnienė E, Marksa M, Bernatoniene J.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Device and Data Access Considerations for Digital Health Studies Using Consumer-Grade Wearables: An Experience-Based Tutorial. [PDF]

Clin Transl Sci
Zhu M, Spencer JD, Chesak S, Romanowicz M, Chauhan M, Dyrbye LN, Croarkin PE, Bobo WV, Athreya AP.   +8 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Exploratory Characterization of Artisanal Royal Jelly Produced by <i>Apis mellifera siciliana</i> Using ¹H-NMR Metabolomics and NIR Spectral Fingerprinting. [PDF]

Foods
Ravagli C, Pasini F, Antonioni V, Cirrito D, Zhu C, Caboni MF, Laghi L.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Trapped honey bees reduce floral visitation on milkweed flowers. [PDF]

Ecology
Jett ID, Yang LH.
europepmc   +1 more source