Results 131 to 140 of about 38,480 (291)

Oral anticoagulation in patients with gastrointestinal bleeding and new‐onset atrial fibrillation: A population‐based registry‐linkage study

Journal of Internal Medicine, Volume 298, Issue 5, Page 450-463, November 2025.
Abstract Background Limited data exist on the prevalence of gastrointestinal bleeding (GIB) in patients with new‐onset atrial fibrillation (AF) and the impact of GIB on the initiation of oral anticoagulation (OAC) therapy. Methods A population‐based registry‐linkage study included all patients diagnosed with new‐onset AF in Finland during 2010–2018 who
Santeri Jolkkonen, Jukka Putaala, Konsta Teppo, Pirjo Mustonen, Jussi Jaakkola, Aapo Aro, Olli Halminen, Ossi Lehtonen, Jari Haukka, Miika Linna, Juha Hartikainen, K. E. Juhani Airaksinen, Mika Lehto   +12 more
wiley   +1 more source

IgG and IgM Anti‐Phosphatidylserine/Prothrombin Complex Antibody Detection May Improve Classification Accuracy of Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Antiphospholipid antibody (aPL) syndrome (APS) classification requires a thrombotic event and detection of lupus anticoagulant (LAC), anticardiolipin antibodies (aCL), or anti–β2‐glycoprotein I (anti‐β2GPI) antibodies on two occasions ≥12 weeks apart. Here, we investigated the utility of anti–phosphatidylserine/prothrombin complex (anti‐PS/PT)
Christina Donath, Sara Kahlown, Liye Suo, Katalin Banki, Andras Perl   +4 more
wiley   +1 more source

Apixaban and clopidogrel in a fixed-dose combination: Formulation and in vitro evaluation

Saudi Pharmaceutical Journal
Fixed-dose combination (FDC) products represent a novel, safe, and cost-effective formulation. Combined use of anticoagulant and antiplatelet medications is common among comorbid cardiovascular patients.
Ni'meh Al-Shami, Hani Naseef, Feras Kanaze   +2 more
doaj   +1 more source

Apixaban triumphs over aspirin for stroke prevention in patients with atrial fibrillation [PDF]

, 2011
Alexandra King
openalex   +1 more source

Characterizing the Healthcare Utilization and Costs of Hereditary Hemorrhagic Telangiectasia

American Journal of Hematology, Volume 100, Issue 10, Page 1722-1735, October 2025.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is the second‐most common inherited bleeding disorder worldwide, afflicting one in 4000–5000 people, and is the most morbid inherited bleeding disorder of women. HHT causes recurrent severe epistaxis, chronic gastrointestinal bleeding, heavy menstrual bleeding, and arteriovenous malformations in the ...
Hanny Al‐Samkari, Tracy J. Mayne, Misty Troutt, Hemant Patle, Marianne Clancy, Eric Duhaime   +5 more
wiley   +1 more source

Dependence of clot structure and fibrinolysis on apixaban and clotting activator

Research and Practice in Thrombosis and Haemostasis
Background: Anticoagulants prevent the formation of potentially fatal blood clots. Apixaban is a direct oral anticoagulant that inhibits factor (F)Xa, thereby impeding the conversion of prothrombin into thrombin and the formation of blood clots.
Rebecca A. Risman, Mitali Shroff, Julie Goswami, Valerie Tutwiler   +3 more
doaj   +1 more source

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

Brain and Behavior, Volume 15, Issue 10, October 2025.
This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi, Benneth Ben‐Azu, Ejayeta Jeroh, Faith B. Friday   +3 more
wiley   +1 more source

Apixaban plasma concentrations before and after catheter ablation for atrial fibrillation.

PLoS ONE
BackgroundCatheter ablation in patients with atrial fibrillation is associated with a transient increase in thromboembolic risk and adequate anticoagulation is highly important.
Rachel Aakerøy, Jan Pål Loennechen, Roar Dyrkorn, Stian Lydersen, Arne Helland, Olav Spigset   +5 more
doaj   +1 more source

Representativeness of the dabigatran, apixaban and rivaroxaban clinical trial populations to real-world atrial fibrillation patients in the United Kingdom: a cross-sectional analysis using the General Practice Research Database [PDF]

, 2012
Sally Lee, Brigitta U. Monz, Andreas Clemens, Martina Brueckmann, Gregory Y.H. Lip   +4 more
openalex   +1 more source

Multiple Biventricular Intracardiac Thrombi—An Unusual Finding in Peripartum Cardiomyopathy: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Peripartum cardiomyopathy (PPCM) is a rare form of heart failure occurring during late pregnancy or within 5 months postpartum, its etiology remaining elusive. While typically characterized by left ventricular dysfunction, it may present with intracardiac thrombi, raising the risk of systemic embolization.
Gidion Edwin, Yohana Mbishi, Baraka Alphonce, John Meda   +3 more
wiley   +1 more source