Results 81 to 90 of about 193,360 (208)

Predictors of clinically significant bleeding in dogs with severe thrombocytopenia: 159 cases (2012‐2021)

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To evaluate risk factors for clinically significant bleeding in dogs with severe thrombocytopenia and to assess whether predictors of bleeding differ between immune thrombocytopenia and other causes, and whether platelet mass is more predictive than platelet count.
G. Smith, E. D. Bennet, A. E. Ridyard
wiley   +1 more source

Oral Lichenoid Lesions in Patients With Dyskeratosis Congenita: A Retrospective Case Series

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Dyskeratosis congenita (DKC) is a rare inherited multisystem disorder primarily affecting the mucocutaneous and hematopoietic systems. Classically, it presents with the ectodermal triad of reticulate skin pigmentation, nail dystrophy, and oral leukoplakia.
Yehuda Zadik   +9 more
wiley   +1 more source

Safety, Pharmacokinetics, and Efficacy Study of Porcine and Rabbit Antithymocyte Globulin in the Treatment of Patients With Severe Aplastic Anemia: A Multicenter, Prospective, Randomized, Open‐Label Clinical Trial [PDF]

open access: yesMedComm (2020)
This prospective trial compared porcine‐ATG and rabbit‐ATG for severe aplastic anemia. Both agents peaked on Day 5, with faster clearance for rabbit‐ATG. Porcine‐ATG induced an early stable neutrophil rise, whereas rabbit‐ATG caused an initial neutrophil drop.
Zhang Y, Zhang Y, Gong Y, Sun Y, He G.
europepmc   +2 more sources

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

Aplastic anemia associated with interferon alpha 2a in a patient with chronic hepatitis C virus infection: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Hepatitis-associated aplastic anemia is a common syndrome in patients with bone marrow failure. However, hepatitis-associated aplastic anemia is an immune-mediated disease that does not appear to be caused by any of the known hepatitis ...
Ioannou Savvas   +3 more
doaj   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

open access: yesTransplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez   +16 more
wiley   +1 more source

APLASTIC ANEMIA

open access: yes, 2013
Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Aplastic Anemia describes a disorder of the clinical syndrome is marked by a deficiency of red blood cells, neutrophils, monocytes and platelets in
Wayan Putu Sutirta Yasa   +2 more
core  

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza   +14 more
wiley   +1 more source

Performance evaluation of a CD34 expression assay by digital PCR in bone marrow harvest from healthy donors

open access: yesTransfusion, EarlyView.
Abstract Background The aim of this study was to investigate a CD34 expression assay as an additional tool for the total nucleated cell (TNC) count assessment in bone marrow harvest (BMH) obtained from healthy donors. Study Design and Methods Samples obtained from bone marrow donors (n = 71) were analyzed for CD34 expression using a digital PCR assay ...
Miguel Waterhouse   +13 more
wiley   +1 more source

Forest plot of HLA-DRB1*15:01 polymorphism and aplastic anemia.

open access: yes, 2016
Forest plot of HLA-DRB1*15:01 polymorphism and aplastic anemia.
Hanti Lu (3111243)   +8 more
core   +1 more source

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