Results 121 to 130 of about 3,923,482 (304)

Age Does Not Affect Respiratory Characteristics in Children With Prader‐Willi Syndrome Before and After Growth Hormone Therapy

Acta Paediatrica, EarlyView.
ABSTRACT Aim Children with Prader‐Willi syndrome (PWS) are at increased risk of both central (CSA) and obstructive sleep apnoea (OSA). Studies examining the effects of growth hormone have focused on older children; however, therapy is often initiated before the age of 2 years.
Michelle Ip, Sze Lut Cheng, Okkes R. Patoglu, Georgina Plunkett, Lauren C. Nisbet, Gillian M. Nixon, Margot J. Davey, Rosemary S. C. Horne   +7 more
wiley   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

Non‐epileptic paroxysmal events in Rett syndrome: A systematic review of case‐based and observational evidence

Developmental Medicine &Child Neurology, EarlyView.
This systematic review identifies and categorizes the spectrum of non‐epileptic paroxysmal events in Rett syndrome. Respiratory disturbances, behavioural episodes, and motor events were the most commonly reported. Improving clinician awareness and diagnostic clarity is key to avoiding unnecessary treatment and enhancing quality of life for individuals ...
Natasha Bhatti, Daniel E. Lumsden
wiley   +1 more source

Impact of a Case‐Based Sleep Apnoea Education on the Knowledge, Attitudes and Confidence of Dental Hygiene Students—A Multicentre Intervention Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective This pilot study aimed to explore knowledge, attitudes and confidence levels of Obstructive Sleep Apnoea (OSA) before and after case‐based education among dental hygiene students. Moreover, to give an international perspective, this study included students from the US and Scandinavia. Methods A longitudinal multicentre study assessed
Ann‐Catrin André Kramer, Bridget Wright, Kristina Berggren, Linda Lundsbakken, Karelle Hopkins, Hanna Ahonen, Ulrika Lindmark   +6 more
wiley   +1 more source

Prevalence of Dental Caries in Persons With or Without Long‐Term Experience of Positive Airway Pressure‐Treated Obstructive Sleep Apnoea

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Oral dryness is common in persons with untreated obstructive sleep apnoea (OSA) as well as in those using positive airway pressure (PAP). OSA with or without PAP treatment could therefore be a risk factor of dental caries. Objectives To describe and compare the prevalence of dental caries among persons with or without PAP‐treated OSA.
H. Ahonen, K. Berggren, C. Kvarnvik, O. Sunnergren, U. Lindmark, A. Broström, M. Stensson   +6 more
wiley   +1 more source

The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects [PDF]

, 2018
Preliminary evidence supports an association between OSA and cardiac dysrhythmias. Negative intrathoracic pressure, as occurring during OSA, may provoke cardiac dysrhythmias.
Camen, Giovanni, Clarenbach, Christian, Kohler, Malcolm, Rossi, Valentina, Sievi, Noriane, Stradling, John, Stöwhas, Anne-Christin   +6 more
core  

Examining the Influence of Glycemic Management During Sleep on Sleep‐Related Bruxism: A Pilot Study

Journal of Oral Rehabilitation, EarlyView.
Stabilisation of blood glucose levels during sleep may improve sleep‐related bruxism (SRB), particularly by suppressing sympathetic nervous system activity. Furthermore, it is expected that these findings will lead to the establishment of new treatment methods for SRB in sleep dentistry.
Tatsuya Taniwaki, Kazuo Okura, Yoshitaka Suzuki, Toyoko Tajima, Akitomo Watanabe, Yoshizo Matsuka   +5 more
wiley   +1 more source

Impulse Configuration in Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea: The Effect of Modifying Pulse Width and Frequency

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Hypoglossal nerve stimulation is an effective treatment option for obstructive sleep apnea (OSA) in positive airway pressure therapy failure. Nonetheless, data regarding the functional effect of modifying stimulation parameters within each electrode configuration are limited.
Armin Steffen, Stephanie Jeschke, Ryan J. Soose, Katrin Hasselbacher, Inke R. König   +4 more
wiley   +1 more source

Case reports of oral appliance therapy on three young adults with Down syndrome and OSA

Journal of Prosthodontics, EarlyView.
Abstract Patients with Down syndrome (DS) have a high incidence of obstructive sleep apnea (OSA) due to hypotonia, weight, underdeveloped midface, and relative macroglossia. This article presents three cases of young adults with DS, who were diagnosed with mild to severe OSA and unable to tolerate positive airway pressure therapy.
Jingjing Zhang, Yuuya Kohzuka, Kathleen M. Bennett, Fernanda R. Almeida   +3 more
wiley   +1 more source

Metrology of two wearable sleep trackers against polysomnography in patients with sleep complaints

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep trackers are used widely by patients with sleep complaints, however their metrological validation is often poor and relies on healthy subjects. We assessed the metrological validity of two commercially available sleep trackers (Withings Activité/Fitbit Alta HR) through a prospective observational monocentric study, in adult patients ...
Justine Frija, Jimmy Mullaert, Laure Abensur Vuillaume, Mathieu Grajoszex, Ruben Wanono, Hélène Benzaquen, Fedja Kerzabi, Pierre Alexis Geoffroy, Boris Matrot, Théo Trioux, Thomas Penzel, Marie‐Pia d'Ortho   +11 more
wiley   +1 more source