Results 141 to 150 of about 3,923,482 (304)

Sex‐Based Differences in Noncommunicable Diseases in Older Adults: Raising the Profile of Older Females

Journal of the American Geriatrics Society, EarlyView.
Aathmika Nandan, Joyce M. Li, Paula A. Rochon   +2 more
wiley   +1 more source

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng, Daniel Lorch, Nancy Hall, Margaret Moline   +3 more
wiley   +1 more source

Cerebral oxygenation responses to obstructive sleep apnea in cognitively normal older adults: a study using simultaneous polysomnography and functional near-infrared spectroscopy

Scientific Reports
Obstructive sleep apnea (OSA) can cause intermittent cerebral hypoxia that may impair brain health. However, widely used clinical indicators such as the Apnea-Hypopnea Index (AHI) and peripheral oxygen saturation (SpO₂) may not accurately capture ...
Chang Hyun Park, Hwan Wook Shim, Hwidon Lee, Chang-Seok Kim, Young-Min Lee   +4 more
doaj   +1 more source

Napping during cognitive behavioural therapy for insomnia: Friends or foes?

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Cognitive and Behavioural Therapy for Insomnia (CBT‐I) is the gold standard treatment for chronic insomnia, with one crucial step being the restriction of time spent in bed. This restriction often intensifies early afternoon sleepiness, leading to a natural gateway for a short recuperative nap, which might foster adherence to CBT‐I over time ...
Brice Faraut, Louise Gaillard, Annabelle Labonne, Julie Margrethe Dubois, Joëlle Adrien, Damien Léger   +5 more
wiley   +1 more source

Diet Reduce Apnea Hypopnea Index (Ahi) Score in Obstructive Sleep Apnea Patient: Systematic Review and Meta-analysis

Journal of Agromedicine and Medical Sciences (AMS)
Obstructive sleep apnea (OSA) is a breathing disorder during sleep that can cause obstruction to the flow of breathing with characteristics such as collapse of the upper airway which can cause breathing to stop, either completely (apnea) or partial ...
Adella Bintang Saputri, Nindya Shinta Rumastika, Muhammad Afiful Jauhani, Wiwien Sugih Utami, Jauhar Firdaus   +4 more
doaj   +1 more source

Resting state functional thalamic connectivity abnormalities in patients with post-stroke sleep apnoea: a pilot case-control study [PDF]

, 2017
OBJECTIVE: Sleep apnoea is common after stroke, and has adverse effects on the clinical outcome of affected cases. Its pathophysiological mechanisms are only partially known.
CALISTRI, VALENTINA, CARAMIA, Francesca, DE LENA, Carlo, DI MASCIO, MARIA TERESA, FIORELLI, Marco, G., RUSSO, MAINERO, Caterina, MINNI, Antonio, SACCHETTI, Maria Luisa, TINELLI, EMANUELE   +9 more
core  

The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial

Journal of Sleep Research, EarlyView.
ABSTRACT Daridorexant, a dual orexin receptor antagonist, is approved for the treatment of insomnia disorder in adults. Approximately 30%–35% of patients with insomnia disorder also have obstructive sleep apnoea (OSA) of any severity. It is unclear whether sleep medications provide safe and effective treatment for insomnia in these patients.
Christopher J. Lettieri, Orestis Briasoulis, Damien Léger, Pierre‐Philippe Luyet, Jean‐Louis Pépin, Stuart F. Quan, Janna Raphelson, Paul Saskin, Atul Malhotra   +8 more
wiley   +1 more source

Obstructive Sleep Apnea in Chronic Obstructive Pulmonary Disease: A Prospective Observational Study

National Board of Examinations Journal of Medical Sciences
Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) frequently coexist as overlap syndrome a condition associated with severe nocturnal hypoxemia, increased exacerbations, higher cardiopulmonary morbidity and ...
M. R. Dhanush Kumar, Aswini Mohan Ram, M. Vinoth Kumar   +2 more
doaj   +1 more source

Effect of Liraglutide on Intermittent Hypoxia‐Induced Metabolic Dysfunction: From Bench to Bedside

Journal of Sleep Research, EarlyView.
ABSTRACT Intermittent hypoxia (IH)‐mediated adipose tissue inflammation with M1 macrophage polarisation plays a key role in the pathogenesis of metabolic diseases in obstructive sleep apnoea (OSA). Effective treatment strategies are so far lacking.
Cliona O'Donnell, Ailbhe King, Guillaume Vial, Emily O'Neill, Shane Crilly, Jonathan D. Dodd, David J. Murphy, Elise Belaidi, Jean‐Louis Pepin, Claire Arnaud, Donal O'Shea, Silke Ryan   +11 more
wiley   +1 more source

Childhood OSAS and Obesity: Prospective Associations of Anthropometric Markers With Objective Sleep Outcomes in the CHAT Trial

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnea syndrome (OSAS) is characterised by episodic upper airway obstruction that occurs during sleep and is common in children with obesity. The aim of the present study was to analyse the association between baseline anthropometric markers and objective sleep quality measures at follow‐up in school‐aged children with OSAS ...
Catalina Ramírez‐Contreras, Verónica Palma Elgueta, Lautaro Briones‐Suárez   +2 more
wiley   +1 more source