Results 201 to 210 of about 3,868,397 (337)

The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Daridorexant, a dual orexin receptor antagonist, is approved for the treatment of insomnia disorder in adults. Approximately 30%–35% of patients with insomnia disorder also have obstructive sleep apnoea (OSA) of any severity. It is unclear whether sleep medications provide safe and effective treatment for insomnia in these patients.
Christopher J. Lettieri   +8 more
wiley   +1 more source

Hypoxic Load and Average Oxygen‐Saturation During Sleep and Wake Are Associated With Cognitive Function in Obstructive Sleep Apnea

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Cognitive processes commonly affected by obstructive sleep apnea (OSA) are more strongly associated with hypoxic load parameters than the apnea‐hypopnea index (AHI). Additionally, lower SpO2 during wake affects cognition, emphasising the need for concurrent assessment with sleep SpO2.
K. Thorisdottir   +7 more
wiley   +1 more source

Effect of Liraglutide on Intermittent Hypoxia‐Induced Metabolic Dysfunction: From Bench to Bedside

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Intermittent hypoxia (IH)‐mediated adipose tissue inflammation with M1 macrophage polarisation plays a key role in the pathogenesis of metabolic diseases in obstructive sleep apnoea (OSA). Effective treatment strategies are so far lacking.
Cliona O'Donnell   +11 more
wiley   +1 more source

Apnea Hypopnea Index, Oxygen Desaturation Index, and QTC Interval in Obstructive Sleep Apnea [PDF]

open access: bronze, 2015
Ștefan Dumitrache-Rujinski   +7 more
openalex   +1 more source

Changes in pharyngeal anatomy and apnea/hypopnea index after a mandibular advancement device. [PDF]

open access: yesSleep Sci, 2022
Cortes-Mejia JM   +6 more
europepmc   +1 more source

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