Results 291 to 300 of about 66,547 (371)
A precision trial case study for heterogeneous treatment effects in obstructive sleep apnea
Canadian Journal of Statistics, Volume 53, Issue 4, December 2025.Abstract Precision medicine tailors treatments to individual patient characteristics, which is especially valuable for obstructive sleep apnea (OSA), where treatment responses vary widely. Traditional trials often overlook subgroup differences, leading to suboptimal recommendations.
Lara Maleyeff +3 more
wiley +1 more source
Clinical Cardiology, Volume 48, Issue 12, December 2025.The CYP3A5 rs776746 CC genotype is a strong biomarker for ticagrelor‐induced dyspnea, conferring a 2.3‐fold higher risk. Genotype‐guided antiplatelet therapy may mitigate this adverse reaction, enabling personalized treatment for ACS patients. ABSTRACT Background Dual antiplatelet therapy with aspirin and a P2Y₁₂ inhibitor is standard for patients with
Yanming Zhang +5 more
wiley +1 more source
Impact of Mask Type on Pharyngeal Opening Pressures During Drug‐Induced Sleep Endoscopy
The Laryngoscope, Volume 135, Issue 12, Page 4976-4982, December 2025.Assessment of the impact of mask type on pharyngeal opening pressures during drug‐induced sleep endoscopy (DISE) is currently lacking. Our study demonstrates that pharyngeal opening pressures at the velum, oropharynx, and tongue base are significantly reduced using nasal vs. full‐face mask techniques.
Leonard E. Estephan +8 more
wiley +1 more source
Body Mass Index and Hypoglossal Nerve Stimulation Outcomes: A Systematic Review and Meta‐Analysis
Laryngoscope Investigative Otolaryngology, Volume 10, Issue 6, December 2025.This systematic review and meta‐analysis evaluated the impact of elevated body mass index (BMI) on outcomes following hypoglossal nerve stimulation (HGNS) for obstructive sleep apnea. Across seven studies, higher BMI, particularly, above the 32 kg/m2 cutoff‐was associated with reduced treatment response rates, though many patients still achieved ...
Coleton Evans +4 more
wiley +1 more source
Parent Reports Versus Objective Behavioral Measures in Pediatric Sleep‐Disordered Breathing
Laryngoscope Investigative Otolaryngology, Volume 10, Issue 6, December 2025.Among children with SDB, we observed limited agreement between parent‐reported behavioral problems and objective assessments of response inhibition. Although parent‐reported inhibitory issues initially showed a weak, statistically significant correlation with performance‐based attention measures in unadjusted analyses, this relationship was mitigated ...
Daniel C. Fong +5 more
wiley +1 more source
0761 Detailed Three-Year Effects of Proximal Targeted Hypoglossal Nerve Stimulation on Apnea-Hypopnea Index in Moderate to Severe Obstructive Sleep Apnea [PDF]
Alan R. Schwartz +14 more
openalex +1 more source
Laryngoscope Investigative Otolaryngology, Volume 10, Issue 6, December 2025.ABSTRACT Objective In adult patients who undergo soft tissue and maxillomandibular advancement (MMA) sleep surgery for obstructive sleep apnea (OSA), we identify preoperative pain diagnoses and postoperative pain medication dispensing patterns by surgery type.
Ghedak Ansari +4 more
wiley +1 more source
A genetic analysis of correlated traits : the apnea hypopnea index and body mass index.
, 2007 Emma K. Larkin
openalex +1 more source