Results 61 to 70 of about 131,972 (267)

The Main Symptoms in Dorsal Sleep Apnea - Hypopnea Syndrome [PDF]

open access: yesApplied Medical Informatics, 2014
OSAHS is a chronic, multifactorial disease, accompanied by significant and complex symptoms. The aim of this study was to evaluate the relationship between OSAHS and dorsal AHI in order to improve early diagnosis of dorsal sleep apnea-hypopnea syndrome ...
Mihaela Alexandra POP   +7 more
doaj  

Obstructive sleep apnea-hypopnea syndrome: Etiology and diagnosis

open access: yesAvicenna Journal of Medicine, 2012
Sleep disordered breathing is a common chronic condition in the general population. This review will highlight the prevalence of different types of sleep apnea in general and obstructive type in particular in the United States and Middle East.
Abdul Ghani Sankri-Tarbichi
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source

Optical Flow-Based Algorithms for Real-Time Awareness of Hazardous Events

open access: yesEng
Safety and security are major priorities in modern society. Especially for vulnerable groups of individuals, such as the elderly and patients with disabilities, providing a safe environment and adequate alerting for debilitating events and situations can
Stiliyan Kalitzin   +2 more
doaj   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano   +6 more
wiley   +1 more source

Prevalence of predictive factors for obstructive sleep apnea in university students [PDF]

open access: yesSleep Science
Objectives: To identify predictive factors for obstructive sleep apnea in university students. Material and Methods: Analytical, observational, cross-sectional study, conducted from August 2018 to February 2019.
Eduardo Rodrigues dos Santos   +3 more
doaj   +1 more source

Semaglutide vs. liraglutide and incidence of diabetes and cardiovascular disease: A target trial emulation using real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) semaglutide and liraglutide are approved for chronic weight management. Both drugs also have favourable effects on the risk of developing diabetes and cardiovascular disease (CVD) compared with placebo, but their comparative effectiveness for these outcomes is unclear.
Ethan J. Cannon   +7 more
wiley   +1 more source

Fentanyl: efectos adversos en anestesia subaracnoidea con bupivacaína

open access: yesRepertorio de Medicina y Cirugía, 2010
Los efectos adversos de los opioides son el resultado de interacciones con sus receptores a nivel cerebral. Cuando se administran por vía intratecal se ha descrito depresión respiratoria, aunque con menor frecuencia que en uso endovenoso.
Luis Eduardo Reyes   +5 more
doaj   +1 more source

Paediatric clonidine medication errors: Findings from a multicentre French study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard   +8 more
wiley   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

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