Results 101 to 110 of about 5,735,361 (325)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Enoc, viajero celeste más allá de la muerte

open access: yesRevista de Filología Románica, 2006
The Bible does not mention the death of Enoch, a fascinating character whom several Enochic traditions depict as revelator of heavenly secrets, inventor of the calendar and the astronomy, celestial scribe and voyager.
Sin autor
doaj  

Keeping Count of the End of the World: A Statistical Analysis of the Historiography, Canonisation, and Historical Fluctuations of Anglophone Apocalyptic and Post-Apocalyptic Disaster Narratives

open access: yesCulture Unbound: Journal of Current Cultural Research, 2015
Over the past decade, apocalyptic and post-apocalyptic disaster narratives seem to have become more popular than ever before. Since its inception in secular form in the first decades of the nineteenth century, however, the genre has experienced a number ...
Jerry Määttä
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Apocalyptic Imaginings

open access: yes, 2019
The thematic section of this issue of JRFM deals with apocalyptic imaginings in literature and film. The articles address issues such as authority, authenticity, belief, imagining social futures, and art as social laboratory.
John Lynch   +8 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Hermeneutics of Biblical Apocalyptic

open access: yes, 2023
U ovome članku iznosimo praktične smjernice za uspješan pristup biblijskoj apokaliptici, naročito Knjizi proroka Daniela i Ivanovom Otkrivenju. Ukratko razmatramo pristupe tumačenju biblijske apokaliptičke literature.
Paulien, Jon
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

“The Cyclone Which is at the Heart of Things”: The Cyclone as Trope of Place and Apocalypse in Queensland Literature

open access: yeseTropic: electronic journal of studies in the tropics, 2016
In order to better understand and respond to the tropics as part of the global environment, we need to accept the unique features of the regional weather, such as cyclones, and be prepared to embrace their larger meaning for life in the tropics.
Chrystopher Spicer
doaj  

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