Results 131 to 140 of about 5,735,361 (325)

Комментарий к стихотворению Пастернака «Последний день Помпеи» [Annotations to Boris Pasternak’s Poem “The Last Day of Pompeii”]

open access: yesSlavica Revalensia
The article offers a close reading and contextual analysis of Boris Pasternak’s poem “The Last Day of Pompeii” (1915). Its title borrowed from Karl Briullov’s famous painting is misleading as it has nothing to do either with the Roman city destroyed by ...
Alexander Dolinin
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Anxiety and Worry about Six Categories of Climate Change Impacts. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Stewart AE, Chapman HE, Davis JBL.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

POST APOCALYPTIC LITERATURE AND THE STATE: SCIENCE FICTION AND STORYWORLDS

open access: yes, 2017
Mary Manjikian and other critics argue that post-911 apocalyptic Literature is anarchic, breaking away from the state through its destruction. This thesis challenges this claim, looking at the state through the abstract form presented by Deleuze and ...
Goforth, Andrew
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Apocalyptic movie - background, forms and function [PDF]

open access: yes, 2011
The bachelor thesis "Apocalyptic movie - background, forms and function" deals the apocalyptic movie phenomenon as a functional element in the occidental civilization since 1920s until now.
Novák, Michal
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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