Results 71 to 80 of about 1,129 (214)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
ENOCH AS AN EXISTENTIAL PHENOMENON OF “WALKING WITH GOD”
Relevance of the research. The figure of Enoch is one of the most enigmatic in the biblical tradition. The brevity of the biblical references to him, combined with the extensive reception in apocalyptic and early Christian literature, makes the ...
Dmytro Rybуdailo
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
In a world of disasters and uncertaintys, post-apocalyptic literature is increasingly attracting the attention of readers and critics. This article examines Anna Kavan’s Ice and Manon Steffan Ros’s The blue book of Nebo, novels set in post-apocalyptic ...
Nguyen Le Khanh Duoc +2 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
In order to better understand and respond to the tropics as part of the global environment, we need to accept the unique features of the regional weather, such as cyclones, and be prepared to embrace their larger meaning for life in the tropics.
Chrystopher Spicer
doaj
To live in the open: the post-apocalyptic chronotope in Frío, by Rafael Pinedo
Unlike traditional approaches to apocalyptic myth, post-apocalyptic fictions focus on narrating what happens after an event conceived as final and, therefore, they are not interested in the causes leading to the collapse of civilization, but what remains
Agustina Giuggia
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

