Results 101 to 110 of about 478,843 (289)

The pH of the skin surface and its impact on the barrier function [PDF]

, 2006
The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Abeck D, Barel AO, Blank HI, Bouwstra JA, Braun-Falco O, Chao SC, Dikstein S, Elias P, Elsner P, Epprecht R, Francomano MA, Gfatter R, Gfatter R, Hartmann AA, Heuss E, Keining E, Korting HC, Korting HC, Korting HC, Korting HC, Krien PM, Menon GK, Mucke H, Naissan O, Ohmann H, Rippke F, Runeman B, Schade H, Schirren CG, Schnyder UW, Schreiner V, Seidenari S, Sparavigna A, Talbert GA, Turner RB, Vahlquist A, Wickett RR, Wilhelm KP, Yosipovitch G, Yosipovitch G, Yosipovitch G, Zlotogorski A   +41 more
core   +1 more source

A giant apocrine hidrocystoma associated with elevated serum carcinoembryonic antigen levels: a case report

Journal of Medical Case Reports, 2019
Background Serum carcinoembryonic antigen levels are often elevated in patients with malignant diseases. However, the etiology of elevated serum carcinoembryonic antigen levels may be extremely difficult to determine considering that this finding may ...
Kazuhiro Matsueda, Toshio Otani, Yusuke Fujioka, Motowo Mizuno   +3 more
doaj   +1 more source

Metastatic cutaneous apocrine adenocarcinoma successfully treated with systemic anti‐androgen therapy—A case report

Clinical Case Reports, 2020
Primary cutaneous apocrine adenocarcinoma (PCAC) is an extremely rare neoplasm involving the sweat glands. Due to a lack of cases, there is no consensus for the systemic treatment of locally advanced or metastatic PCAC.
Fanny Collette, Marc Hamoir, Pascal Van Eeckhout, Philippe D’Abadie, Thierry Duprez, Sandra Schmitz, Jean‐Pascal Machiels   +6 more
doaj   +1 more source

Topographical variations in the skin barrier and their role in disease pathogenesis

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 7, Page 1228-1238, July 2025.
Unlike the gut, the skin appears uniform at first glance. However, histological and molecular biological research has revealed significant regional variations in the composition and function of its main barrier elements. In this review, we describe the topographical differences of four barrier elements in healthy skin: microbiome, chemical, physical ...
Z. Dajnoki, A. Kapitány, K. Eyerich, S. Eyerich, D. Törőcsik, A. Szegedi   +5 more
wiley   +1 more source

Longitudinal Assessment of QT Apex in Tumor‐Bearing Dogs Receiving Doxorubicin Monotherapy

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background The cardiac morphologic and functional derangements induced by doxorubicin (DOX) are referred to as DOX‐induced cardiotoxicity (DOX‐IC). Prolongation of the QT apex (QTa) has been identified as a potential marker for the early detection of DOX‐IC in humans. Objectives Describe changes in QTa that occur in dogs with cancer undergoing
Keita Kitagawa, Jacob Ryave, Robert A. Sanders, Ji‐Hyun Lee, Zhongyue Zhang, Paulo Vilar Saavedra   +5 more
wiley   +1 more source

Is mechanical stress an important pathogenic factor in hidradenitis suppurativa? [PDF]

, 2012
Hidradenitis suppurativa (HS) is a chronic of recurrent, inflammatory, follicular disease that usually presents after puberty with painful deep-seated, inflamed lesions in the inverse skin areas of the body.
Prens, E.P. (Errol), Winter, K. (K.) de, Zee, H.H. (Hessel) van der   +2 more
core   +2 more sources

Axillary apocrine carcinoma associated with apocrine adenoma and apocrine gland hyperplasia.

Acta dermatovenerologica Croatica : ADC, 2007
Apocrine carcinomas represent a rare group of tumors with a potential for destructive local invasion, regional and distant metastases, and are equally common in both sexes. A case of a 79-year-old woman with axillary apocrine carcinoma associated with apocrine adenoma and apocrine gland hyperplasia is presented. To our knowledge, this is the first case
Bujas, Tatjana, Pavić, Ivana, Leniček, Tanja, Mijić, August, Krušlin, Božo, Tomas, Davor   +5 more
openaire   +2 more sources

Apocrine-Eccrine Carcinomas: Molecular and Immunohistochemical Analyses [PDF]

, 2013
Apocrine-eccrine carcinomas are rare and associated with poor prognosis. Currently there is no uniform treatment guideline. Chemotherapeutic drugs that selectively target cancer-promoting pathways may complement conventional therapeutic approaches ...
Cosper, Arjola K., Deng, April, Dias-Santagata, Dora, Hoang, Mai P, Horick, Nora K., Iafrate, Anthony John, Le, Long Phi, Mihm, Martin Charles, Nguyen, Anh Thu, Pawlak, Amanda C., Selim, M. Angelica   +10 more
core   +1 more source

Retroauricular apocrine hidrocystoma: A very rare case report

Acta Oto-Laryngologica Case Reports
Apocrine hidrocystoma is a rare benign cystic tumor arising from the secretory portion of the apocrine sweat glands. Although these lesions are typically found on the face, particularly at the eyelid margins, their occurrence in the retroauricular region
Sinan Ghavami, Caroline Rieu-Chevreau
doaj   +1 more source

Case Report: A Pathological Odyssey in Primary Cutaneous Apocrine Carcinoma [version 3; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2023
Apocrine carcinoma is an extremely rare malignant cutaneous neoplasm that usually arises in areas with a high density of apocrine glands. Diagnosis can be challenging as tumours share histological and immunophenotypic characteristics with them.
Dr. Suhit Naseri, Sunita Vagha, Samarth Shukla, Dr. Sourya Acharya   +3 more
doaj