Results 81 to 90 of about 89,064 (218)

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Panax quinquefolium saponin decreases atherosclerosis in ovariectomized ApoE^-/- mice via regulating estrogen receptor α. [PDF]

Chin Med
Chen L, Shi JH, Ma XJ, Chai H, Wei KK, Yang Z, Tan Y, Huang HB, Shi DZ, Qu H.   +9 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Now is the time: the need to update guidance to expand access to <i>APOE</i> genetic testing. [PDF]

Front Dement
Uhlmann WR, Chan AK, Goldman JS.
europepmc   +1 more source

''Υστερία (Φρόυντ, πριν και μετά)''

, 2017
Η ιστορική ανασκόπηση της Υστερίας, από την αρχαιότητα μέχρι και τη σύγχρονη εποχή. Από την περιπλανώμενη μήτρα, υπεύθυνη για την Υστερία που εμφανίζεται αποκλειστικά και μόνο στο γυναικείο φύλο, στην θεώρησή της, κατά τον 19ο αιώνα, ως αποτέλεσμα δυσλειτουργίας του νευρικού συστήματος που μπορεί να εμφανιστεί και στα δύο φύλα.
openaire   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

iNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

The time interval from amyloid to tau PET positivity varies by age, sex and APOE-ε4 status. [PDF]

J Prev Alzheimers Dis
Milà-Alomà M, Hausle I, Petersen KK, Thropp P, Schindler SE, Tosun D, Alzheimer’s Disease Neuroimaging Initiative.   +6 more
europepmc   +1 more source

The concept of ''disability'' in architecture as a power and ideology problem

, 2016
The concept of disability, which is well accepted around the world and seem to be a statement of positive discrimination at first, requires to become a current issue as an equality problem in architecture and society today. In fact, the definition of disability and its intellectual basis are major and still invisibile obstacles to obtain equal rights ...
Saltoğlu, Selma, Öksüz, Aysun Aydın
openaire   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

The lysophosphatidylcholine-HIF-1α axis enhances apolipoprotein E sialylation and promotes electronegative LDL accumulation. [PDF]

iScience
Chan HC, Chan HC, Wang LF, Chan ML, Huang WC, Bender D, Ko YM, Yu ML, Ke GM, Chou MC, Liu CK, Ke LY.   +11 more
europepmc   +1 more source