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Current Opinion in Lipidology, 2021
Purpose of review The 2019 European Society of Cardiology/European Atherosclerosis Society Guidelines concluded that apolipoprotein B (apoB) was a more accurate measure of cardiovascular risk and a better guide to the adequacy of lipid lowering than low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein ...
Sniderman, A. +2 more
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Purpose of review The 2019 European Society of Cardiology/European Atherosclerosis Society Guidelines concluded that apolipoprotein B (apoB) was a more accurate measure of cardiovascular risk and a better guide to the adequacy of lipid lowering than low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein ...
Sniderman, A. +2 more
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Clinics in Laboratory Medicine, 2006
This article reviews the evidence showing that apolipoprotein (apo) B and A-1 are superior to the conventional cholesterol indices as analytes in laboratory practice, indices of the lipoprotein-related risk for vascular disease, and measures of the adequacy of low-density lipoprotein-lowering therapy.
Santica M. Marcovina, Allan D. Sniderman
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This article reviews the evidence showing that apolipoprotein (apo) B and A-1 are superior to the conventional cholesterol indices as analytes in laboratory practice, indices of the lipoprotein-related risk for vascular disease, and measures of the adequacy of low-density lipoprotein-lowering therapy.
Santica M. Marcovina, Allan D. Sniderman
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Apolipoprotein B polymorphism and altered apolipoprotein B concentrations in Congolese blacks
Clinical Genetics, 1991The immunoreactivity of apolipoprotein B (apo B) in plasma obtained from 238 unrelated black African male subjects from the People's Republic of Congo was analysed by non‐competitive Enzyme Linked‐Immunosorbent Assay (ELISA) with monoclonal BIP 45 anti‐LDL antibody.
M. Qafli +16 more
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Clinica Chimica Acta, 2022
Elevated lipid levels during pregnancy have been shown to be related to the risk of preterm birth. Despite the importance of apolipoprotein (Apo) in lipid metabolism and transportation, evidence regarding apolipoprotein levels during pregnancy and preterm birth is still limited. Therefore, we aim to investigate the associations between maternal ApoA-1,
Qing, Liu +6 more
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Elevated lipid levels during pregnancy have been shown to be related to the risk of preterm birth. Despite the importance of apolipoprotein (Apo) in lipid metabolism and transportation, evidence regarding apolipoprotein levels during pregnancy and preterm birth is still limited. Therefore, we aim to investigate the associations between maternal ApoA-1,
Qing, Liu +6 more
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Structure and biosynthesis of apolipoprotein B
American Heart Journal, 1987Apolipoprotein (apo) B100 copy deoxyribonucleic acid (cDNA) has been cloned and sequenced. The total sequence of apo B100 messenger ribonucleic acid has been revealed by the work from our group, as well as other groups. The sequence spans 13,689 nucleotides from the initiation to the stop codon.
Margit Wettesten +7 more
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Apolipoprotein B and Lipoprotein Metabolism
1985Publisher Summary This chapter describes apolipoprotein B (apoB) and lipoprotein metabolism. ApoB-containing lipoproteins enter the circulation primarily as chylomicrons and very low-density lipoproteins (VLDL), but entry into other lipoprotein densities following secretion includes entry into intermediate density lipoprotein, low-density ...
Janet D. Sparks, Charles E. Sparks
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Genetic abnormalities in apolipoprotein B
Trends in Cardiovascular Medicine, 1991Recent studies have demonstrated that mutations in the apolipoprotein (apo-) B gene can cause significant alterations in blood cholesterol levels. A variety of apo-B gene mutations that prevent the translation of a full-length apo-B molecule can lead to low blood cholesterol levels. A missense mutation in the apo-B gene has been described that prevents
Stephen G. Young, MacRae F. Linton
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Cerebrovascular Diseases, 2020
<b><i>Aim:</i></b> Prospective studies indicate that apolipoprotein (apo) measurements predict coronary heart disease risk. However, few population-based follow-up studies have addressed the predictive value of apo measurements in stroke risk.
San Lin You +5 more
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<b><i>Aim:</i></b> Prospective studies indicate that apolipoprotein (apo) measurements predict coronary heart disease risk. However, few population-based follow-up studies have addressed the predictive value of apo measurements in stroke risk.
San Lin You +5 more
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Rat apolipoprotein B differs in solubility properties from human apolipoprotein B
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990Apolipoprotein B (ApoB) in general is known as an insoluble protein in aqueous buffers without the initial aid of denaturing agents. However, following the total delipidization of rat plasma low-density lipoproteins, a considerable portion (28.2 +/- 3.0%) of rat ApoB was found directly soluble in an aqueous buffer, N-ethylmorpholine acetate (pH 7.3) as
David L. Stiers +2 more
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Phosphorylation-dephosphorylation of apolipoprotein B
1986Publisher Summary There is little doubt of the physiologic importance of apolipoprotein B (apoB). In addition to being essential for the secretion of very low-density lipoprotein (VLDL), apoB plays a fundamental role in targeting cholesterol, as a component of LDL, to tissues via specific high-affinity receptors.
Roy A. Borchardt, Roger A. Davis
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