Results 151 to 160 of about 45,443 (285)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins [PDF]

open access: yes, 2017
Agosta   +207 more
core   +2 more sources

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Lipid Profile Alterations Across Coronary Heart Disease, Metabolic Syndrome, and Nephrotic Syndrome

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
CHD, MetS, and NS exhibit distinct dyslipidemia patterns. TC, TG, ApoB, ApoE, and sdLDL‐C are key markers for disease differentiation. This study found that elevated TC and sdLDL‐C were key pathogenic factors in CHD. In contrast, TG and ApoB played significant roles in the pathogenesis of MetS.
Shudong Tan   +3 more
wiley   +1 more source

A Study on the Characteristics of Sonazoid Contrast‐Enhanced Ultrasound in the Transitional Phase for Common Focal Liver Lesions and Its Value in Differential Diagnosis

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objective To investigate the value of transitional phase characteristics on Sonazoid contrast‐enhanced ultrasound (S‐CEUS) in the differential diagnosis of common focal liver lesions (FLLs). Materials and Methods This prospective multicenter study enrolled 122 participants with FLLs from 8 medical centers between December 2023 and March 2025. The study
Yunhao Luo   +10 more
wiley   +1 more source

Effects of Changes in Metabolic Syndrome Status on Cognitive Function: A 10‐Year Study in a Middle‐Aged Population

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The long‐term cumulative impact of metabolic syndrome (MS) on cognitive decline remains uncertain. This study investigated how changes in MS status over 10 years relate to cognition and whether sex modifies this relationship. A total of 766 participants (mean baseline age: 54 years) from the Kaohsiung Atherosclerosis Longitudinal Study were ...
Kelly Lim   +6 more
wiley   +1 more source

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