Results 151 to 160 of about 55,604 (311)
What's New? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song+10 more
wiley +1 more source
11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) converts inactive 11-keto derivatives to active glucocorticoids within tissues and may play a role in the metabolic syndrome (MS).
Guoping Li+4 more
doaj
Localization of the structural gene for human apolipoprotein A-I on the long arm of human chromosome 11. [PDF]
Peter Cheung+5 more
openalex +1 more source
Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang+8 more
wiley +1 more source
Acidification of the intimal fluid: the perfect storm for atherogenesis
Atherosclerotic lesions are often hypoxic and exhibit elevated lactate concentrations and local acidification of the extracellular fluids. The acidification may be a consequence of the abundant accumulation of lipid-scavenging macrophages in the lesions.
Katariina Öörni+6 more
doaj
Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4). [PDF]
Sotirios K. Karathanasis+3 more
openalex +1 more source
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu+8 more
wiley +1 more source
An immunoassay procedure that quantifies remnant-like particle (RLP) cholesterol in human blood plasma has shown considerable promise as a clinically applicable risk marker for atherosclerotic disease.
Elisa Campos+7 more
doaj