Results 181 to 190 of about 45,443 (285)

Accelerating Medicines Partnership® Parkinson's Disease Proteomics: A Comprehensive Resource for Advancing Parkinson's Disease Research

Movement Disorders, EarlyView.
Abstract Background Recent advances in proteomic profiling have enabled its use as a powerful approach in elucidating molecular mechanisms underlying Parkinson's disease, enabling the identification of disease‐associated protein alterations and candidate biomarkers for diagnosis, progression, and therapeutic response.
Victoria J. Dardov, Aparna Vasanthakumar, Ameya Kulkarni, Niveda Sundararaman, Rakhi Pandey, Preeti Bais, Jennifer E. Van, Maria Quinton, Barry Landin, David Vismer, Bradford Casey, Matt Bookman, Willy Nojopranoto, Erin Teeple, Can Kayatekin, Rajaraman Krishnan, Richard Hargreaves, Guhan Nagappan, S. Pablo Sardi, Sri Ramulu Pullagura, Christine Swanson‐Fischer, Accelerating Medicines Partnership Parkinson's Disease (AMP PD) Proteomics Working Group   +21 more
wiley   +1 more source

People living with HIV on modern antiretrovirals do not display a pro-atherogenic lipid profile and have similar body composition compared to healthy controls. [PDF]

HIV Med
Savinelli S, Heeney A, Tinago W, Garcia Leon AA, McGettrick P, Cotter AG, Walsh I, Fitzgibbon M, Sabin CA, Mallon PWG, Feeney ER, HIV UPBEAT study group.   +11 more
europepmc   +1 more source

Lipid management: maximising reduction of cardiac risk [PDF]

, 2013
Gonna, H, Ray, KK, Webb, J
core   +1 more source

The Genomic Evolution of Early‐Stage Non‐Small Cell Lung Cancer

Medicine Advances, EarlyView.
This study provides a comprehensive overview of the genomic landscape of early‐stage non‐small cell lung cancer, identifying the 4q12 deletion as a potential exclusive biomarker for the “oncogenic switch” from pre‐invasive to invasive lesions. It delineates that while EGFR and TP53 mutations act as early truncal drivers, the progressive increase in ...
Huatao Tang, Yang Zhang, Haiquan Chen
wiley   +1 more source

Plasma apolipoproteins and memory function in alcohol use disorder: Findings in male C57BL/6J mice and men suggest a role for APOAI. [PDF]

Alcohol Clin Exp Res (Hoboken)
Escudero B, Kreifeldt M, Fleck K, Lopez C, Contet C, Orio L.   +5 more
europepmc   +1 more source

Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders

Neuroprotection, EarlyView.
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan, Roshan S. Raghavan, Dawn Li Wei Koh, Wing Yeng Tan, Igor Iezhitsa, Renu Agarwal   +5 more
wiley   +1 more source

Editorial: Lipidology at the Dawn of a New Era. [PDF]

Diabetes Metab Syndr Obes
Corral P.
europepmc   +1 more source

Dissecting the genetic architecture of lipids, lipoproteins and apolipoproteins, Lessons from twin studies [PDF]

, 1999
Boomsma, D.I., Doornen, L.J.P. van, Snieder, H.   +2 more
core   +2 more sources

Adipose Tissue‐Derived Small Extracellular Vesicles in Plasma Reveal Molecular Circuitries Underlying Glucose Intolerance

Obesity, EarlyView.
ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Shalini Mishra, Yixin Su, Ashish Kumar, Sangeeta Singh, Brian S. Finlin, Fang‐Chi Hsu, Jingyun Lee, Cristina M. Furdui, Philip A. Kern, Swapan K. Das, Gagan Deep   +10 more
wiley   +1 more source

Lipid Profile, Apolipoproteins, and Impulsivity in First Episode Mania. [PDF]

Cureus
Behera R, Swain SP, Sahu P, Nayak S, Mohapatra D.   +4 more
europepmc   +1 more source