Results 11 to 20 of about 55,323 (311)
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
Vision, 2022 Serum apolipoproteins have been reported as a more significant marker for diabetic retinopathy (DR) compared with serum cholesterols. This article aims to review the associations between serum cholesterols and apolipoproteins, and the presence and ...
Soefiandi Soedarman +3 more
doaj +1 more source
Antiphospholipid antibodies in healthy Serbian middle-aged subjects: Preliminary data [PDF]
Journal of Medical Biochemistry, 2022 Background: The investigation of the prevalence of the IgG and the IgM isotypes of anticardiolipin (aCL) and antib2glycoprotein I (ab2gpI) Abs in healthy Serbian middleaged subjects was the main goal of our study.
Bećarević Mirjana B. +3 more
doaj +1 more source
An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins
Molecules, 2020 Adipokines and apolipoproteins are key regulators and potential biomarkers in obesity and associated diseases and their quantitative assessment is crucial for functional analyses to understand disease mechanisms.
Laura Krieg +9 more
doaj +1 more source
Nanomaterials, 2020 Apolipoproteins are critical structural and functional components of lipoproteins, which are large supramolecular assemblies composed predominantly of lipids and proteins, and other biomolecules such as nucleic acids.
Skylar T. Chuang +2 more
doaj +1 more source
Molecular Dynamics Simulation of Apolipoprotein E3 Lipid Nanodiscs [PDF]
arXiv, 2023 Nanodiscs are binary discoidal complexes of a phospholipid bilayer circumscribed by belt-like helical scaffold proteins. Using coarse-grained and all-atom molecular dynamics simulations, we explore the stability, size, and structure of nanodiscs formed between the N-terminal domain of apolipoprotein E3 (apoE3-NT) and variable number of 1,2-dimyristoyl ...
arxiv
Aqueous Humor Apolipoprotein Concentration and Severity of Diabetic Retinopathy in Type 2 Diabetes
Mediators of Inflammation, 2022 An imbalance of plasma apolipoproteins has been linked to diabetic retinopathy (DR); however, there is scarce information regarding their presence in the aqueous humor (AH) and their role in DR.
Lucia Saucedo +4 more
doaj +1 more source
Molecules, 2021 Oxidative modifications of HDLs and LDLs by myeloperoxidase (MPO) are regularly mentioned in the context of atherosclerosis. The enzyme adsorbs on protein moieties and locally produces oxidizing agents to modify specific residues on apolipoproteins A-1 ...
Catherine Coremans +5 more
doaj +1 more source
Degradation of human apolipoprotein B‐100 by apolipoprotein(a)
FEBS Letters, 1993 Human plasma low density lipoproteine (LDL) contain a very high molecular weight protein termed apoB‐100 (M r = 550,000). In many samples of LDL, minor components designated as apoB‐74 (M r = 407,000) and apoB‐26 (M r = 145,000) are present. It has been shown that they can arise as a result of proteolytic degradation of apoB‐100.
V.V. Tertov, T.M. Chulkova
openaire +3 more sources
Apolipoprotein mimetics in cancer
Seminars in Cancer Biology, 2021 Peptides have many advantages over traditional therapeutics, including small molecules and other biologics, because of their low toxicity and immunogenicity, while still exhibiting efficacy. This review discusses the benefits and mechanism of action of apolipoprotein mimetic peptides in tumor biology and their potential utility in treating various ...
Delk, Samuel C +4 more
openaire +5 more sources