Results 51 to 60 of about 45,443 (285)
The extent to which lipid and apolipoprotein (apo) concentrations in tissue fluids are determined by those in plasma in normal humans is not known, as all studies to date have been performed on small numbers of subjects, often with dyslipidemia or ...
M.N. Nanjee +3 more
doaj +1 more source
New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects [PDF]
Objective: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein A1 ...
Azize Şener +5 more
core +2 more sources
Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. [PDF]
Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish panels of serum protein biomarkers representative of active TB patients and their household contacts who were either infected (LTBI)
Anibarro, L +11 more
core +2 more sources
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source
Amphipathic α-helices of exchangeable apolipoproteins have shown to play crucial roles in the formation of infectious hepatitis C virus (HCV) particles through the interaction with viral particles.
Takasuke Fukuhara +15 more
doaj +1 more source
Lipid and Protein Transfer between Nanolipoprotein Particles and Supported Lipid Bilayers. [PDF]
A nanolipoprotein particle (NLP) is a lipid bilayer disc stabilized by two amphipathic "scaffold" apolipoproteins. It has been most notably utilized as a tool for solubilizing a variety of membrane proteins while preserving structural and functional ...
Coleman, Matthew A +4 more
core
Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. [PDF]
Cell entry of hepatitis C virus, pseudoparticles (HCVpp) and cell culture grown virus (HCVcc), requires the interaction of viral glycoproteins with CD81 and other as yet unknown cellular factors.
Boullier, Agnès +6 more
core +1 more source
Coarse‐grained MD simulations capture the effects of liposome composition and size on protein adsorption onto the liposome surface, in agreement with experiments. Liposome‐protein interactions are energetically stabilized by the replacement of abundant proteins with high‐affinity proteins on the liposome surface through electrostatic and hydrophobic ...
Hwankyu Lee
wiley +1 more source
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn +30 more
core +3 more sources
Apolipoprotein £ and Epilepsy [PDF]
The overall frequencies of the apolipoprotein f2, f3 and f4 alleles in the epilepsy patients were no different to those of the control group (Table 1). Subgroups consisting of patients with either an unknown aetiology for epilepsy (71% of patients), a family history of epilepsy (21% of patients), idiopathic generalized epilepsy, or cryptogenic partial ...
E S, Kilpatrick +3 more
openaire +2 more sources

