Results 291 to 300 of about 13,250,277 (360)

Movement of apolipoprotein B into the lumen of microsomes from hepatocytes is disrupted in membranes enriched in phosphatidylmonomethylethanolamine.

, 1993
Antonio E. Rusiñol, Eric Chan, Jean E. Vance   +2 more
openalex   +1 more source

Assessing the causal relationships between circulating metabolic biomarkers and breast cancer by using mendelian randomization. [PDF]

Front Genet
Wang B, Ling Y, Zhang H, Yang M.
europepmc   +1 more source

Comparison of Model‐Predicted and Observed Evinacumab Pharmacokinetics and Efficacy in Children Aged < 5 Years With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C) in patients with homozygous familial hypercholesterolemia (HoFH). Herein, we report pharmacokinetic and efficacy analyses of evinacumab in < 5‐year‐old patients with HoFH.
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Katy C. Norman, Richard T. George, Xue‐Qiao Zhao, Robert Pordy, Daniel Garcia, Wendy S. Putnam, Geetha Raghuveer, Brian W. McCrindle, Elena Fornari, Ivo Baric, Shubha Srinivasan, Melissa Diamond, Eliot A. Brinton, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +18 more
wiley   +1 more source

Effects of bezafibrate on apolipoprotein B metabolism in type III hyperlipoproteinemic subjects.

, 1990
Chris J. Packard, Richard J. Clegg, Marek H Dominiczak, A R Lorimer, J. Shepherd   +4 more
openalex   +1 more source

Apolipoproteins, lipids, lipid-lowering drugs and risk of amyotrophic lateral sclerosis and frontotemporal dementia: a meta-analysis and Mendelian randomisation study. [PDF]

J Neurol
Chalitsios CV, Ley H, Gao J, Turner MR, Thompson AG.   +4 more
europepmc   +1 more source

Use of Model‐Based Meta‐Analysis to Inform the Design of Early Clinical Trials of Anti‐Amyloid Beta Therapies in Alzheimer's Disease

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT To inform an efficient development of new investigational anti‐amyloid beta (anti‐Aβ) monoclonal antibodies (mAbs), a modeling‐and‐simulation‐based strategy was proposed. A general modeling framework that links drug exposures to the time course of amyloid plaque removal and amyloid‐related imaging abnormalities characterized by edema and ...
Sagar S. Bachhav, Ana Victoria Ponce‐Bobadilla, Diana Clausznitzer, Sven Stodtmann, Hao Xiong   +4 more
wiley   +1 more source

Human apolipoprotein B signal sequence variants confer a secretion-defective phenotype when expressed in yeast.

, 1994
Stephen L. Sturley, Philippa J. Talmud, Robert Brasseur, Michael R. Culbertson, Steve E. Humphries, Alan Attie   +5 more
openalex   +1 more source

Amyloid-forming property of the N-terminal 1-70 residues of human apolipoprotein A-IV. [PDF]

Sci Rep
Namba N, Danjo T, Kitagawa Y, Naito Y, Ohgita T, Shimanouchi T, Saito H.   +6 more
europepmc   +1 more source

Angelica dahurica Polysaccharides Ameliorate Colitis by Reducing the Restriction of Gut Microbiota‐Derived Imidazole Propionate on PPAR‐γ Signaling Activation

Phytotherapy Research, EarlyView.
ABSTRACT Angelica dahurica radix (ADR), the root of the botanical family Apiaceae (genus Angelica, species Angelica dahurica (Hoffm.)), has been used to treat colitis in clinical practice. The immunomodulatory effects of ADR are attributed to its polysaccharides (RP). However, its mechanism of action has not been elucidated.
Jingyi Hu, Feng Xu, Lei Zhu, Yuan Cui, Ryan Au, Yanan Li, Yiheng Tong, Hong Shen   +7 more
wiley   +1 more source

Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions. [PDF]

J Proteome Res
Solosky AM, Claudio IM, Chappel JR, Kirkwood-Donelson KI, Janech MG, Bland AM, Gulland FMD, Neely BA, Baker ES.   +8 more
europepmc   +1 more source