Results 311 to 320 of about 12,469,641 (375)

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Engineering Fusion Proteins for Nanomedicine-Based Cytokine Therapy. [PDF]

Bioconjug Chem
de Dreu A, de Bruin K, Hokke AM, Schrijver DP, Beelen DNH, Verhalle LM, Clavijo Perez MC, Anbergen T, Versteeg I, Maas R, Zwolsman RC, Grao-Roldán C, Bartelet B, Trines MM, Hoorn D, Ros G, Toner YC, Kluza E, Beldman T, Pérez-Medina C, Netea MG, Merkx M, van der Meel R, Mulder WJM.   +23 more
europepmc   +1 more source

Beyond PD‐1: Mechanisms of Resistance to Checkpoint Blockade in Classical Hodgkin Lymphoma and Next‐Generation Immune Strategies

European Journal of Haematology, EarlyView.
ABSTRACT PD‐1 inhibitors have reshaped the treatment landscape of classical Hodgkin lymphoma, yet a substantial proportion of patients exhibit primary or acquired resistance driven by tumor‐intrinsic alterations, immunosuppressive microenvironmental signals, metabolic constraints, and EBV‐mediated modulation.
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Association of Periodontal Condition With Serum C-Reactive Protein Levels: The Role of Serum Apolipoproteins' Concentration. [PDF]

J Clin Periodontol
Haro A, Saxlin T, Suominen AL, Jula A, Ylöstalo P.   +4 more
europepmc   +1 more source

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina, Laura Abraira, Daniel Campos‐Fernández, Manuel Quintana, Elena Fonseca, Samuel López‐Maza, Sofía Lallana, Anna Penalba, Anna Rosell, Júlia Valor‐Blanquer, Clara Sanz, Manuel Toledo   +11 more
wiley   +1 more source

A comparative transcriptomics analysis of mammalian and non-mammalian acute kidney injury (AKI) models. [PDF]

Front Cell Dev Biol
Hawkins MR, Cervera D, Tang TM, Wingert RA.   +3 more
europepmc   +1 more source

Alcohol consumption and risk of dementia: a systematic review and meta‐analysis

Internal Medicine Journal, EarlyView.
Abstract To examine the relationship between alcohol intake and the risk of developing dementia, we conducted a comprehensive search of PubMed, Embase, Cochrane Library and Web of Science databases for relevant studies up to July 22, 2024. The quality of the original studies was appraised utilising the Newcastle‐Ottawa Scale (NOS).
Ren Zhang, Baitao Li, Yue Miao
wiley   +1 more source

Dysfunctional high-density lipoprotein: an updated review. [PDF]

Front Cardiovasc Med
Ouyang FW, Chiang HH, Hsu WL, Tsai MH, Huang CY, Remaley AT, Akyol O, Chen CH.   +7 more
europepmc   +1 more source

Association of tubular injury with lipid metabolism: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhao K, Qian L, Ma X.
europepmc   +1 more source