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Induction of fatty liver in cows by ethionine administration and concomitant decreases of serum apolipoproteins B-100 and A-I concentrations.

American Journal of Veterinary Research, 1992
Ethionine, an analogue of methionine, induces fatty liver in rats by inhibiting protein synthesis, including that of apolipoproteins in liver. Ethionine was administered to cows to elucidate the participation in fatty liver development of impaired ...
Eiji Uchida   +2 more
semanticscholar   +1 more source

Structural comparison of human apolipoproteins B-48 and B-100.

Biochemistry, 1987
In this study we have investigated the structural relationship between human apolipoproteins B-48 and B-100 by comparing protein structure and by comparing nucleotide sequence from intestinal and hepatic cDNA clones. Sequences from intestinal and hepatic
D. Hardman   +9 more
semanticscholar   +1 more source

Associations between maternal mid-pregnancy apolipoprotein A-1, apolipoprotein B, apolipoprotein B/apolipoprotein A-1 ratio and preterm birth

Clinica Chimica Acta, 2022
Elevated lipid levels during pregnancy have been shown to be related to the risk of preterm birth. Despite the importance of apolipoprotein (Apo) in lipid metabolism and transportation, evidence regarding apolipoprotein levels during pregnancy and preterm birth is still limited. Therefore, we aim to investigate the associations between maternal ApoA-1,
Qing, Liu   +6 more
openaire   +2 more sources

Stability of plasma total cholesterol, triglycerides, and apolipoproteins B and A-I during the early postmortem period.

Journal of Forensic Sciences, 1988
The stability of plasma lipids and apolipoproteins during the early postmortem period was studied by taking four duplicate blood samples from eight cadavers 2, 6, 12, and 24 h after death. The bodies were kept at +4 degrees C.
T. Särkioja   +4 more
semanticscholar   +1 more source

Metabolism of high-density lipoprotein apolipoproteins in Tangier disease.

New England Journal of Medicine, 1978
To define the metabolic defect in Tangier disease, we studied the kinetics of [125I]-high-density lipoprotein apolipoproteins (apolipoproteins A-I and A-II) in 11 normal subjects, two obligate heterozygotes, and two homozygotes.
E. Schaefer   +6 more
semanticscholar   +1 more source

Structure and biosynthesis of apolipoprotein B

American Heart Journal, 1987
Apolipoprotein (apo) B100 copy deoxyribonucleic acid (cDNA) has been cloned and sequenced. The total sequence of apo B100 messenger ribonucleic acid has been revealed by the work from our group, as well as other groups. The sequence spans 13,689 nucleotides from the initiation to the stop codon.
Margit Wettesten   +7 more
openaire   +3 more sources

The relation of apolipoproteins A-I and B in children to parental myocardial infarction.

New England Journal of Medicine, 1986
Clinical studies suggest that serum levels of apolipoproteins A-I and B may be more strongly related to coronary artery disease than are their respective lipoprotein-cholesterol fractions.
D. Freedman   +5 more
semanticscholar   +1 more source

Lipids, lipoproteins and apolipoproteins AI, AII, B, CII, CIII and E in newborns.

Biology of the Neonate, 1991
In this study lipid and apolipoprotein patterns were investigated at birth and compared with those of adults. In cord sera, cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol were 38.2, 46.
M. Averna   +7 more
semanticscholar   +1 more source

Apolipoprotein B and Lipoprotein Metabolism

1985
Publisher Summary This chapter describes apolipoprotein B (apoB) and lipoprotein metabolism. ApoB-containing lipoproteins enter the circulation primarily as chylomicrons and very low-density lipoproteins (VLDL), but entry into other lipoprotein densities following secretion includes entry into intermediate density lipoprotein, low-density ...
Janet D. Sparks, Charles E. Sparks
openaire   +3 more sources

Genetic abnormalities in apolipoprotein B

Trends in Cardiovascular Medicine, 1991
Recent studies have demonstrated that mutations in the apolipoprotein (apo-) B gene can cause significant alterations in blood cholesterol levels. A variety of apo-B gene mutations that prevent the translation of a full-length apo-B molecule can lead to low blood cholesterol levels. A missense mutation in the apo-B gene has been described that prevents
Stephen G. Young, MacRae F. Linton
openaire   +3 more sources

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